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Medicine composition for preventing and treating chemotherapy stomatitis and application thereof

A composition and stomatitis technology applied in the field of pharmaceutical compositions for the prevention and treatment of chemotherapeutic stomatitis, which can solve the problems of unfavorable clinical large-scale promotion, complicated use, and high price, and achieve remarkable effects, low cost, and low cost of prevention and treatment. Effect

Inactive Publication Date: 2014-06-25
QINGDAO STOMATOLOGICAL HOSPITAL
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Among these treatment plans, some are more complicated to use, while others are more expensive, which is not conducive to large-scale clinical promotion.

Method used

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  • Medicine composition for preventing and treating chemotherapy stomatitis and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0015] Prescription of herbal medicine: 280g of black petunia, 280g of trigeminal bitter root, 90g of southern star, 330g of diffusa, 60g of broadwood, 200g of comfrey root, 200g of fat sea, 110g of roasted licorice.

[0016] Preparation method: Weigh the prescribed amount of black petunias, trigeminal bitter root, southern star, hedyotis diffusa, broadwood, comfrey root, fat sea and roasted licorice, wash and remove impurities, dry and crush; Add water to the above-mentioned granular medicinal materials to cover the medicinal surface 2cm, soak for 1-1.2h, remove the medicinal materials, put them in a multi-functional extraction tank, add water and decoct twice, add 10 times the amount of water for the first time, decoct for 2 hours, take the decoction solution, filtered, add 8 times the amount of water for the second time, decoct for 1 hour, take the two decoctions and combine, filter, concentrate to a concentrated solution with a relative density of 1.15g / mL at 90°C; the conc...

Embodiment 2

[0018] Prescription of herbal medicine: 240g of black petunia, 250g of trigeminal bitter root, 100g of southern star of tiger palm, 350g of hedyotis diffusa, 60g of broadwood, 180g of comfrey root, 150g of fat sea, 120g of roasted licorice.

[0019] Preparation method: Weigh the prescribed amount of black petunias, trigeminal bitter root, southern star, hedyotis diffusa, broadwood, comfrey root, fat sea and roasted licorice, wash and remove impurities, dry and crush; Add water to the above-mentioned granular medicinal materials to cover the medicinal surface 2cm, soak for 1-1.2h, remove the medicinal materials, put them in a multi-functional extraction tank, add water and decoct twice, add up to 8 times the amount of water for the first time, decoct for 2 hours, take the decoction solution, filtered, add 8 times the amount of water for the second time, decoct for 1 hour, take the two decoctions and combine, filter, concentrate to a concentrated solution with a relative density ...

Embodiment 3

[0021] Prescription of herbal medicine: 300g of black petunia, 330g of trigeminal bitter root, 120g of southern star of tiger palm, 400g of hedyotis diffusa, 80g of broadwood, 250g of comfrey root, 200g of fat sea, 100g of roasted licorice.

[0022] Preparation method: Weigh the prescribed amount of black petunias, trigeminal bitter root, southern star, hedyotis diffusa, broadwood, comfrey root, fat sea and roasted licorice, wash and remove impurities, dry and crush; Add water to the above-mentioned granular medicinal materials to cover the medicinal surface 2cm, soak for 1-1.2h, remove the medicinal materials, put them in a multi-functional extraction tank, add water and decoct twice, add up to 8 times the amount of water for the first time, decoct for 2 hours, take the decoction solution, filtered, add 6 times the amount of water of the medicinal materials for the second time, decoct for 1 hour, take the two decoctions and combine them, filter, concentrate to a concentrated s...

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Abstract

The invention discloses a medicine composition for preventing and treating chemotherapy stomatitis and an application thereof. The medicine composition is prepared from the following Chinese medicine raw materials in parts by weight: 24-33 parts of black semen pharbitidis, 24-33 parts of evodia lepta root, 6-12 parts of pedate pinellia rhizome, 28-40 parts of oldenlandia diffusa, 4-8 parts of costus root, 15-25 parts of alkanet, 15-25 parts of scaphium scaphigerum and 8-15 parts of honey-fried licorice root. The medicine composition disclosed by the invention has the advantage of remarkable effect on preventing and treating chemotherapy stomatitis, meanwhile the prevention and treatment cost is low, and the medicine dependency of patients is high.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine, and in particular relates to a pharmaceutical composition for preventing and treating chemotherapeutic stomatitis and its application. Background technique [0002] It is one of the most common and painful side effects in cancer patients receiving chemotherapy. The mucous membrane of the patient's oral lesion area was congested, with slightly convex soft white dots scattered, and the latter white dots merged to form white spots. The main clinical symptoms are spontaneous severe burning, edema, ulceration, and severe pain in the oral cavity, which affect the patient's speech and eating. The degree of pain not only affects the nutritional intake and quality of life of patients, but can also induce mumps, otitis media, and even severe systemic infections. [0003] According to reports, the incidence of stomatitis in chemotherapy patients is as high as 66%, up to 88%. After ch...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8884A61P1/02
Inventor 朱鲲王娟
Owner QINGDAO STOMATOLOGICAL HOSPITAL
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