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Traditional Chinese medicinal composition for bringing down fever and relieving pain and application thereof

An antipyretic and analgesic, composition technology, applied in the field of antipyretic and analgesic traditional Chinese medicine composition and its use, can solve problems such as unfavorable patient recovery, side effects and the like

Inactive Publication Date: 2014-07-02
FUJIAN UNIV OF TRADITIONAL CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] On the other hand, when treating various inflammations, patients often have symptoms of pain and fever. Therefore, it is often necessary to take painkilling, antispasmodic and cooling drugs at the same time, and these drugs often have considerable side effects , which is not conducive to the recovery of patients

Method used

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  • Traditional Chinese medicinal composition for bringing down fever and relieving pain and application thereof
  • Traditional Chinese medicinal composition for bringing down fever and relieving pain and application thereof
  • Traditional Chinese medicinal composition for bringing down fever and relieving pain and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0033] 100g sarcocarpus, 500g Houttuynia cordata, 100g sinensis, add 70% ethanol 8 times the weight of the medicinal materials and reflux extraction twice, each time for 1.5h. The extracts were combined, ethanol was recovered, concentrated into a clear ointment with a relative density of 1.25-1.30 (60°C thermal test), and dried to obtain 82 g of therapeutic active ingredients.

Embodiment 2

[0035] Add 500g of sarcophagus, 100g of Houttuynia cordata, 500g of sinensis grass, add 50% ethanol 10 times the weight of the medicinal materials, and reflux extraction for 3 times, each time for 1h. Combine the extracts, recover ethanol, concentrate into a clear paste with a relative density of 1.05-1.15 (60°C thermal measurement), add the concentrated solution to the pretreated D101 macroporous resin column, absorb it, and wash with 2 times the column volume of water After stripping, it was eluted with 3 times the column volume of 70% ethanol, the ethanol eluted part was collected, the ethanol was recovered under reduced pressure, and concentrated into a liquid extract, which was spray-dried to prepare 68 g of therapeutic active ingredients.

Embodiment 3

[0037] Take 300g of sargassum, 200g of houttuynia, 200g of sinensis, add 12 times the amount of water to reflux and extract 3 times, each time for 2h. Combine the extracts, depressurize into a clear paste with a relative density of 1.05-1.15 (60°C thermal measurement), add it to the pretreated AB-8 macroporous resin column, and absorb it; after elution with 3 times the column volume of water Then eluted with 4 times column volume of 50% ethanol, collected the ethanol eluted part, reclaimed ethanol, and concentrated into a clear paste, spray-dried to prepare 41g of active ingredient.

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Abstract

The invention discloses a traditional Chinese medicinal composition for bringing down fever and relieving pain and application thereof. The traditional Chinese medicinal composition contains a therapeutically effective ingredient and a pharmaceutically acceptable carrier, wherein the therapeutically effective ingredient is prepared from the following components in parts by weight: 1-3 parts of glabrous sarcandra herb, 1-2 parts of houttuynia cordata and 1-2 parts of carpet bugle. Pharmacological experiments prove that the traditional Chinese medicinal composition has functions of resisting bacteria, resisting inflammation, bringing down fever and relieving pain, and has a synergic bacteriostatic action when being combined with amoxicillin; in clinical, the composition can be used for preparing medicines for treating mild and moderate infectious diseases and serve as an auxiliary medicine for biotic; the traditional Chinese medicinal composition disclosed by the invention is expected to solve adverse reactions caused by excessive use of the biotic and prevent or delay generation of drug resistant strains.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition which can be used as mild and moderate infectious disease treatment medicine or antibiotic auxiliary medicine and its application. Background technique [0002] Various mild and moderate infectious diseases caused by pathogens, including such as pharyngitis, tonsillitis, sinusitis, otitis media, periodontitis, acute bronchitis, acute exacerbation of chronic bronchitis, pneumonia, skin and soft tissue infection, simple urinary Road infection (cystitis), complicated urinary tract infection, acute pyelonephritis, and rectal infection are clinically recognized and frequently-occurring diseases, which bring pain to the lives of patients. Clinically, various mild and moderate infectious diseases are mainly treated with antibiotics, and the correct use of antibiotics can usually achieve better curative effect. It has been 80 years since Fleming published the paper "On the Antibacterial Effec...

Claims

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Application Information

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IPC IPC(8): A61K36/78A61P29/00A61P31/00
Inventor 吴符火梁一池陈强李富艳
Owner FUJIAN UNIV OF TRADITIONAL CHINESE MEDICINE
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