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Multi-row dropping head device with pressure-dividing disc special for preparing big dropping pill of over 100mg

A pressure divider and dripper technology, which is applied in the direction of making medicines into special physical or taking forms, can solve the problems of easy collision and deformation, increase the resistance of liquid medicine, and reduce production efficiency, so as to prevent collision deformation , Reduce processing difficulty, reduce the effect of liquid resistance

Active Publication Date: 2014-09-17
JIANGXI JIMINKEXIN PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The existing commercially available large drop pill production equipment, such as the drop pill machine produced by "Yantai Baiyaotai Traditional Chinese Medicine Technology Co., Ltd." in Yantai City, Shandong Province, uses the above-mentioned utility model patent 200520018541. A dripper device for preparing dripping pills, for dripping large dripping pills, its shortcoming is that the arrangement of the drippers is to arrange the drippers equidistantly on the outer circumference of the disc, and use this dripping pill machine to drip Making large drop pills, the production capacity is low, at most 20-24 large pills can be dropped every 5-7 seconds, the production cycle is long, the relative energy consumption is large, and the working hours are wasted
[0006] In addition, in the dripper devices currently available on the market, the dripper and the dripper are not integrated, but are composed of a single dripper screwed on the dripper. During the production process, the dripper and the production equipment are easy to collide with each other and deform, which increases the risk of drug loss. Liquid resistance, reducing production efficiency

Method used

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  • Multi-row dropping head device with pressure-dividing disc special for preparing big dropping pill of over 100mg
  • Multi-row dropping head device with pressure-dividing disc special for preparing big dropping pill of over 100mg
  • Multi-row dropping head device with pressure-dividing disc special for preparing big dropping pill of over 100mg

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0033] Embodiment 1, dripper device

[0034] The dripper device involved in the present invention mainly consists of an upper cover (1) of the dripper device, a fixed plug (2), a medicinal liquid pressure plate (3), a rubber pad (4), a lower cover of the dripper device (5), The drip nozzle of the inner ring, the drip nozzle of the outer ring (6), and the liquid medicine flow area (7) are composed.

[0035] The connection relationship of its various components is as follows: between the dripper device upper cover (1) and the dripper device lower cover (5) is the liquid medicine flow area (7), and the liquid medicine pressure plate (3) passes through the fixing bolt (2) Installed on the lower cover (5) of the dripper device, rubber pads (4) are installed on both sides of the lower cover (5) of the dripper device, and the lower cover (5) of the dripper device is provided with an inner ring drip nozzle and Outer ring drip-tip (6).

[0036] Wherein, the drip nozzles of the inner ...

Embodiment 2

[0038] Embodiment 2, performance comparison of different dripper devices

[0039] The dripper device of the present invention is compared with existing devices, and its performance is investigated.

[0040] experimental method:

[0041]On the same dripping pill machine, use the drip tray of application number 2005100535892, the drip tray of application number 2005200185413 and the drip tray of the patent of the present invention to drip the same medicinal liquid respectively, and the results are as follows:

[0042] Test Results:

[0043]

[0044] Experimental result shows: the quantity that the present invention produces drop pill per minute is obviously more than existing device, and production speed is fast, and cost is low; Small difference in pellet weight, complete appearance, moderate viscosity and so on.

Embodiment 3

[0045] The preparation process of embodiment 3, dropping pills

[0046] Adopt the currently commercially available dripping pill machine, and its dripper device adopts the double-row dripper device with liquid medicine dividing plate of the present invention to produce Liuwei Dihuang dripping pills, the specification is 300mg)

[0047] Take the prepared liquid of Liuwei Dihuang dripping pills, put them in the drip irrigation of the dripping pill machine, and seal the drip irrigation. The dripper device of the present invention (the installation method of the dripper device: first fix the medicinal liquid pressure plate on the lower cover of the dripper, place a silicone sealing ring on the lower cover of the dripper, install the dripper on the lower cover of the dripper, Connect the upper cover of the dripper and the lower cover of the dripper to make it sealed, that is) connected to the drip irrigation, open the stirring paddle in the drip irrigation, so that the liquid medic...

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PUM

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Abstract

The invention belongs to the field of medicine manufacturing machine equipment and particularly relates to a multi-row dropping head device with a pressure-dividing disc special for preparing a big dropping pill of over 100mg. The dropping head device comprises the following parts: a dropping head device upper cover (1), a fixing bolt (2), a liquid medicine pressure-dividing disc (3), a rubber cushion (4), a dropping head device lower cover (5), an inner circle of dropping nozzle, an outer circle of dropping nozzle (6) and a liquid medicine flowing area (7).

Description

technical field [0001] The invention belongs to the field of pharmaceutical machinery and equipment, and in particular relates to a multi-row dripper device with a liquid medicine dividing plate specially used for preparing large dripping pills of more than 100 mg. Background technique [0002] Dropping pills use solid dispersion technology to heat and melt the active ingredient of the drug and the pharmaceutically acceptable carrier as the matrix (it can be a melt, emulsion or suspension) and drop it into an immiscible condensate. In the drug, the oral preparation of a pharmaceutical composition is formed by rapidly shrinking the liquid drug droplet under the high-temperature state under the tension generated on the surface when it is suddenly cooled to form a pellet, and then condensed and solidified. Compared with conventional oral preparations, there are essential differences in the drop pills prepared by utilizing the above principles. [0003] Existing drop pill prepa...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61J3/06
Inventor 杨铁军强振君马利雄邹武斌
Owner JIANGXI JIMINKEXIN PHARMA
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