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Radix ginseng wall-broken preparation

A technology of red ginseng and preparation, which is applied in the field of traditional Chinese medicine, can solve the problems of easy loss of drug effect, low stability, and easy oxidation of broken wall powder, and achieves improved utilization of active ingredients, good stability, and easy The effect of moisture absorption and oxidation

Active Publication Date: 2014-09-24
ZHONGSHAN ZHONGZHI PHARMA GRP
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The technical problem to be solved by the present invention is to overcome the defects in the prior art that the broken wall powder is easy to be oxidized, the stability is not high, and the drug effect is easy to lose, and to provide a red ginseng broken wall preparation

Method used

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  • Radix ginseng wall-broken preparation

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0029] Take the red ginseng medicinal material, coarsely pulverize it into a coarse powder of about 100 meshes, and then superfinely pulverize it into a powder in which 90% of the particles in the ultrafine powder have a particle size less than or equal to 32 μm, add ethanol-water solution (the mass fraction of ethanol is 70 %) soft material by wet method, the ratio of solution to superfine powder is 0.54:1 (by weight), after mixing, pre-installed 10-mesh sieve, the extrusion speed is 50r / min, and the extrusion force is 1MPa to make wet The granules and wet granules are placed in a hot air circulation oven, set the drying temperature to 75°C, and dried for 2.5 hours until dry.

[0030]

[0031] Note: The full score is 10.

Embodiment 2

[0033] Take the red ginseng medicinal material, coarsely pulverize it into a coarse powder of about 100 meshes, and ultrafinely pulverize it into a powder in which 90% of the particles in the ultrafine powder have a particle size less than or equal to 32 μm, add ethanol-water solution (the mass fraction of ethanol is 80 %) soft material by wet method, the ratio of solution to superfine powder is 0.60:1 (by weight), after mixing, pre-installed 10-mesh sieve, the extrusion speed is 50r / min, and the extrusion force is 0.9MPa. Wet granules, wet granules are transferred to a vacuum microwave drying oven, set the drying temperature to 45°C, and dried for 0.75h until dry.

[0034]

[0035] Note: The full score is 10.

Embodiment 3

[0037] Take the red ginseng medicinal material, coarsely pulverize it into a coarse powder of about 100 meshes, and ultrafinely pulverize it into a powder in which 90% of the particles in the ultrafine powder have a particle size less than or equal to 32 μm, add ethanol-water solution (the mass fraction of ethanol is 95 %) soft material by wet method, the ratio of solution to superfine powder is 0.75:1 (by weight), after mixing, pre-installed 30-mesh sieve, the extrusion speed is 80r / min, and the extrusion force is 0.3MPa. Wet granules, wet granules are transferred to a hot air circulation oven, set the drying temperature to 65°C, dried for 2.5 hours until dry, and the whole granules are sieved to obtain the red ginseng wall-broken preparation.

[0038]

[0039] Note: The full score is 10.

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Abstract

The invention relates to the technical field of Chinese medicine preparations, and in particular relates to a radix ginseng wall-broken preparation. The radix ginseng wall-broken preparation is prepared as follows: crushing radix ginseng into wall broken powder, then granulating by use of an ethanol-water wet method, extruding for forming at a certain rotating speed and drying, and the prepared radix ginseng wall-broken preparation is high in bioavailability, strong in stability, and good in disintegration.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine, and in particular relates to a red ginseng wall-breaking preparation. Background technique [0002] Ultrafine pulverization technology is a new technology developed rapidly in recent years. Most of the active ingredients in Chinese herbal medicines are distributed in the cells. Conventional decoction pieces can only release part of the active ingredients, and the utilization rate of active ingredients is 10-30%. However, using the wall-breaking crushing technology, such as crushing Chinese herbal medicine pieces to 300 mesh About 86.7% of the cell wall breaking rate will increase the dissolution of the active ingredients in the medicinal materials, greatly enhance its efficacy, and the utilization rate of the active ingredients will be above 90%, so as to reduce the amount of medicinal materials used and protect the medicinal materials resources. The quality increases the efficacy. H...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/258A61K9/16A61K47/10A61J3/00A61K125/00
Inventor 成金乐赖智填陈勇军钱锦花梁学良
Owner ZHONGSHAN ZHONGZHI PHARMA GRP
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