Medical protecting irrigation solution and preparation method thereof
A rinsing solution and medical technology, applied in the field of medical devices, can solve the problems of the decline of bacterial survival and reproduction ability, and do not involve these aspects, and achieve the effects of improving wound microcirculation, preventing wound adhesion and scar formation, and promoting wound healing.
Active Publication Date: 2014-10-08
SHIJIAZHUANG YISHENGTANG MEDICAL SUPPLIES
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Problems solved by technology
[0011] However, it is well known that a humid environment is often accompanied by aggravation of bacterial infection. Bacteria are more likely to survive and reproduce in a humid environment, and the ability of bacteria to survive and reproduce in a dry environment is greatly reduced.
[0012] Therefore, the moisturizing, lubricating and antibacte
Method used
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Experimental program
Comparison scheme
Effect test
Embodiment 11
[0045] Embodiment 11~15 Preparation Example for Adjusting the Addition of Phosphate Buffer, Glycerin and Sodium Chloride
[0046] Weigh 1.0 g of carboxymethyl chitosan with a weight average molecular weight of 20,000, dissolve carboxymethyl chitosan in 100 ml of water under stirring, add sodium chloride, glycerin, and phosphate buffer to dissolve, and sterilize and filter , to obtain a medical protective flushing solution, the addition of sodium chloride, phosphate buffer, glycerol and pH measured values in the solution are shown in Table 3.
[0047] Table 3 Examples 11-15 add sodium chloride, phosphate buffer, glycerin addition amount and pH value
[0048] .
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Abstract
The invention relates to a medical protecting irrigation solution. The irrigation solution comprises the following components in percentage by weight: 0.5-5 percent of carboxymethyl chitosan, 0.70-0.9 percent of sodium chloride and the balance of water, wherein the weight-average molecular weight of the carboxymethyl chitosan is 5000-80000. The medical protecting irrigation solution can play roles in irrigating and cleaning a traumatic wound, and has the effects of keeping the wound wet and smooth, preventing adhesion of a wound and generation of a scar, inhibiting bacteria on the wound from growing, and the like; furthermore, the process is simple, and the irrigation solution can be stored stably and has less possibility of being degraded.
Description
technical field [0001] The invention belongs to the field of medical devices, and in particular relates to a medical flushing liquid and a preparation method thereof. Background technique [0002] Due to the mechanized industrial age, injuries caused by various accidents are increasing day by day. How to better promote wound healing of patients and reduce their pain is the direction of many people's efforts. [0003] In the process of surgical trauma treatment, medical workers often use various measures to deal with it, such as hemostatic agents, anti-inflammatory agents, wound rinses, etc. Currently, the commonly used medical rinse solution is sodium chloride injection, which has good fluidity , clean and pollution-free, which is of great significance for debridement during surgery. [0004] However, sodium chloride injection still has some deficiencies as a medical flushing solution. For example, no moisturizing properties, no lubricating properties, and no antibacterial...
Claims
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Patent Timeline
Login to view more IPC IPC(8): A61K33/14A61K47/04A61K47/36A61K47/10A61P41/00A61P17/02A61P31/04A61K31/722
Inventor 刘胜军高明李素哲张彪李国付李玉东李勇
Owner SHIJIAZHUANG YISHENGTANG MEDICAL SUPPLIES
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