113 results about "Irrigation Solutions" patented technology

This invention relates to a method of inhibiting tumor cell adhesion, pain, and inflammation at a wound during a surgical procedure by delivering an irrigation solution containing a tumor cell anti-adhesion agent and a plurality of additional agents to an operative site during the surgical procedure. In addition, methods of inhibiting tumor cell attachment and implantation during a surgical procedure as well as inhibiting tumor metastasis during a surgical procedure are also provided.

Solutions for perioperative intraocular application by continuous irrigation during ophthalmologic procedures are provided. These solutions include multiple agents that act to inhibit inflammation, inhibit pain, effect mydriasis (dilation of the pupil), and/or decrease intraocular pressure, wherein the multiple agents are selected to target multiple molecular targets to achieve multiple differing physiologic functions, and are included in dilute concentrations in a balanced salt solution carrier.

A dispenser cap for combination with a standard flexible irrigation solution bottle to make a portable wound irrigation dispenser includes a collar threadably engageable with the irrigation bottle, and closed at one end by a wall defining a tubular neck. The tubular neck forms a flow path from the bottle to a splash shield including a nozzle for directing irrigation solution. A valve is disposed in the flow path for opening and closing this flow path. A combination apparatus includes the flexible irrigation solution bottle, which may be inverted and squeezed in order to direct a jet of cleansing liquid into a wound. A single use version of the apparatus includes a valve which is closed in a storage and shipping configuration of the apparatus, and an indicator which is freed within the transparent or translucent flexible bottle when the valve is opened, thus irreversibly indicating that the apparatus has been used. An alternative embodiment of the apparatus includes a safety valve which also prevents misuse of the apparatus without the splash shield installed.

An infusion pressure monitoring system for a phacoemulsification or vitrectomy machine to be operated by a health care provider includes an irrigation path configured to carry an irrigation solution to a surgical site and a fluid sensor configured to detect a fluid parameter in the irrigation path. An input device receives a variable fluid flow command from the health care provider commanding an irrigation fluid flow through the irrigation path at a flow rate corresponding to the command. A controller communicates with both the fluid sensor and the input device. The controller determines an expected fluid pressure value and a dynamically variable threshold pressure value based upon the variable fluid flow command.

A method and solution for perioperatively inhibiting a variety of pain, inflammation, spasm and restenosis processes resulting from cardiovascular or general surgical, therapeutic and diagnostic procedures. The solution preferably includes multiple pain and inflammation inhibitory agents, including at least one local anesthetic agent, and spasm inhibitory agents at dilute concentration in a physiologic carrier, such as saline or lactated Ringer's solution. Specific preferred embodiments of the solution of the present invention for use in cardiovascular and general vascular procedures also include anti-restenosis agents.

An irrigation and aspiration device comprises a probe and an aspiration sleeve that ensheathes the probe. The aspiration sleeve prevents the insertion of the probe beyond a desired distance, thereby preventing perforation of the apex of a root canal or wound, and also aspirates any excess irrigation solution and free debris. The device can be used for endodontic and periodontal procedures, penetrating or tract wound irrigation, open or superficial non-penetrating wound irrigation, and irrigation during specialty surgeries in endoscopic, opthalmology, gynecology, orthopedic surgery, and other specialty surgeries.

A method and solution for perioperatively inhibiting a variety of pain and inflammation processes at wounds from general surgical procedures including oral/dental procedures. The solution preferably includes multiple pain and inflammation inhibitory at dilute concentration in a physiologic carrier, such as saline or lactated Ringer's solution. The solution is applied by continuous irrigation of a wound during a surgical procedure for preemptive inhibition of pain and while avoiding undesirable side effects associated with oral, intramuscular, subcutaneous or intravenous application of larger doses of the agents. One preferred solution to inhibit pain and inflammation includes a serotonin2 antagonist, a serotonin3 antagonist, a histamine antagonist, a serotonin agonist, a cyclooxygenase inhibitor, a neurokinin1 antagonist, a neurokinin2 antagonist, a purinoceptor antagonist, an ATP-sensitive potassium channel opener, a calcium channel antagonist, a bradykinin1 antagonist, a bradykinin2 antagonist and a mu -opioid agonist.

A medical compress for use in treating chronic wounds includes a non-woven textile fabricated from air laid fibers containing a superabsorbent material. The superabsorbent material is enclosed by a knitted mesh which can be formed to the shape of the wound. An irrigation solution is preferably contained by the compress to keep the wound irrigated and to encourage healing.

An irrigation and aspiration device comprises a probe and an aspiration sleeve that ensheathes the probe. The aspiration sleeve prevents the insertion of the probe beyond a desired distance, thereby preventing perforation of the apex of a root canal or wound, and also aspirates any excess irrigation solution and free debris. The device can be used for endodontic and periodontal procedures, penetrating or tract wound irrigation, open or superficial non-penetrating wound irrigation, and irrigation during specialty surgeries in endoscopic, ophthalmology, gynecology, orthopedic surgery, and other specialty surgeries.

The subject invention provides novel, inexpensive, and highly effective methods and devices for convenient and effective wound irrigation. In one embodiment the subject invention provides a discharge means for a reservoir housing containing irrigation solution wherein the discharge means has one or more specifically designed nozzles through which a sufficient volume of the irrigation solution can pass at an appropriate pressure.

A triple natural polymer viscoelastic composition is disclosed. By combining glucosamine sulfate (“GS”), sodium hyaluronate (“HA”) and chondroitin sulfate (“CS”), the triple natural polymer viscoelastic compositions of this invention can provide a viscoelastic agent at a surgical site that not only serves as a protective agent to ocular tissues, but that can also act as an agent to alleviate pain and inflammation associated with ocular surgery. Embodiments of this invention can comprise GS combined with existing HA/CS viscoelastic agents. Embodiments of this invention can also comprise GS and CS in combination with an irrigation solution. Further, to enhance retention time at the site of an intra-articulate application of an embodiment of this invention, the following biodegradable polymers may also be included in an embodiment of the compositions of the present invention: cellulose derivatives (e.g., hydroxypropylmethylcellulose, ethylcellulose, caboxymethylcellulose, etc.), carbopol, citosan, and collagen.

The present invention relates to medical hemostatic adhesion-resisting irrigating solution for operation period. It is made up by using injection water as carrier, using non-water-soluble chitosan or water-soluble chitosan or carboxymethyl chitosan as main raw material and adding NaCL or mannilol or glycine as auxiliary material through a certain preparation process.

An isotonic irrigation solution for wounds, surgical incisions and as a lavage, the irrigation solution comprising saline, antimicrobial, chelator, surfactant and collagenous biological enhancer.

A set of a first and a second preparation are intended to be mixed before or during an endodontic treatment to form an endodontic irrigation solution. The first preparation includes an oxidizing agent. The second preparation includes antibacterial nanoparticles treated to slow their oxidation by the oxidizing agent. The antibacterial nanoparticles are, for example, encapsulated in shells in a hybrid core-shell structure. In one variation, the antibacterial nanoparticles are made from an alloy of at least two elements, one of the elements being more resistant to oxidation than the other.

The invention discloses an external auditory canal irrigation device. The external auditory canal irrigation device comprises an irrigation solution tube and an inflatable bag, wherein the inflatable bag communicates with the tail end of the irrigation solution tube through an air inlet pipe; a check valve is arranged on the air inlet pipe; an irrigation pipe is arranged at the head end of the irrigation solution tube; the irrigation pipe comprises a first pipe body, a bellows body and a second pipe body which are connected sequentially, the first pipe body communicates with the head end of the irrigation solution tube, a pull rope is arranged on the second pipe body, an adjusting shaft rotationally connected with the irrigation solution tube is arranged in the position, close to the tail end, of the outer wall of the irrigation solution tube, and a free end of the pull rope is connected with the adjusting shaft. The external auditory canal irrigation device adopting the structure has the advantages that the device is convenient to operate, irrigation is thorough and an external auditory canal wall cannot be damaged.

The present invention provides a unique method and apparatus for improving crop yield through the use of an inventive irrigation solution to inhibit surface pathogens, improved water penetration and increase crop production and market quality. In a presently preferred embodiment, the inventive method comprises the steps of producing a gaseous mixture of negatively charged ionized air including from about 50 parts per million to about 4,000 parts per million ozone, from about 1,000 parts per million to 20,000 parts per million oxygen ions, and from 2,000 to about 50,000 parts per million nitrogen oxides from ambient air; effecting direct contact between the ionized air gaseous mixture and a supply of water by means of a submicron injector to produce a gaseous solution for treatment of irrigation water to be applied to agricultural crops. Accordingly, by treating the crops during irrigation the inventive process promotes plant growth and inhibits harmful insects and parasites on plants above ground.

The invention provides a primer composition for detecting legionella in clinical and environmental specimens. The primer composition comprises a pair of primers (shown in the Seq ID No.1-2) for PCR specific amplification of a gene mip and a pair of primers (shown in the Seq ID No.3-4) for PCR specific amplification of 16S rRNA. The invention also provides a detection kit containing the primer composition. A test on 320 groups of phlegm and alveolar irrigation solutions of pneumonia patients and 210 groups of environmental water specimens proves that the primer composition has singularity of 100% and a lowest detection limit of 2*10<1> cfu/ml. The dual PCR system can be successfully used in bacterial strain identification and clinical and environmental specimen detection. The PCR detection method built based on the dual PCR system has the characteristics of simpleness, fastness and reliability and can be widely used in epidemiology preliminary investigation, environmental water monitoring and clinical specimen detection.

The present invention provides hydrogen-containing physiological saline, a preparation method and uses, wherein the hydrogen-containing physiological saline comprises physiological saline and elemental hydrogen dissolved in the physiological saline. The preparation method comprises: preparing physiological saline; and introducing hydrogen gas with a purity of not less than 99.9999% into the physiological saline at a temperature of 20 DEG C to achieve the supersaturated state of the hydrogen gas in the physiological saline so as to obtain the hydrogen-containing nasal cavity care solution. According to the present invention, the hydrogen-containing physiological saline can be used for preparing the nasal cavity irrigation solution, can promote the recovery of physiological functions of nasal mucosa through anti-oxidation and anti-inflammatory effects, and can be effectively applied after pathogenic bacteria infection, allergy, surgical trauma and other damage on nasal mucosa functions;and the hydrogen-rich saline for nasal cavity irrigation is conveniently to use, can be directly used for nasal cavity irrigation, and can be used for the nasal mucosa physiological function recoveryof chronic rhinitis, sinusitis, allergic rhinitis, nasal tumors and other diseases.

The fluid control device is attached to tubes carrying irrigation solution to form the system. The control device splits the flow through a fiber optic scope and a fluid control unit. The fluid control unit controls rate of flow and direction. The flow of fluid into the joint, out of the joint, or no flow is easily controlled by the operator. The device also allows more than one inflow, useful when using suction or suction shaving devices. The increased flow prevents collapse of a joint space and maintains clear visualization. The fluid flow relies on gravity by having a fluid reservoir positioned at a high point in the system.