Application of andrographolide

A technology of andrographolide and medicine, which is applied in the application field of plant extracts, can solve the problems of not finding andrographolide, etc., and achieve the effect of protecting gastric mucosa, inhibiting Helicobacter pylori, and good curative effect

Active Publication Date: 2014-10-29
SHIJIAZHUANG YILING PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there is no literature report on the use o

Method used

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  • Application of andrographolide
  • Application of andrographolide

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0056] Embodiment 1: tablet preparation

[0057] Weigh 100g of andrographolide, add 100g of microcrystalline cellulose, 200g of lactose, mix well, add croscarmellose sodium, mix well, granulate with a 24 mesh sieve, dry at 70°C, granulate, add 1% magnesium stearate, mixed evenly, compressed into 1000 tablets.

Embodiment 2

[0058] Embodiment 2: capsule preparation

[0059] Weigh andrographolide 100g, add microcrystalline cellulose 50g, add crospovidone 10g, lactose 130g, mix well, add 5% povidone K30 aqueous solution 30ml, add water 15ml, fully stir, mix well, use Granulate with a 24-mesh sieve, dry at 70°C, granulate, add 1% magnesium stearate, mix well, and pack into capsules to obtain 1000 capsules.

Embodiment 3

[0060] Embodiment 3: Granule preparation

[0061] Weigh 100g of andrographolide raw material, add 500g of sucrose, 2500g of dextrin, fully mix, add 180ml of water, fully stir, mix evenly, granulate with a 24 mesh sieve, dry at 70°C, granulate, and pack into 500 bags.

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PUM

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Abstract

The invention discloses application of andrographolide, and belongs to the field of medicine application. The medicine is used to protect gastric mucosa, is capable of mitigating gastric mucosal injury caused by drinking, helicobacter pylori and abnormal gastric acid secretion, is suitable for long-term administration, and has no obvious side effect.

Description

technical field [0001] The invention belongs to the field of medicine application, and in particular relates to the application of plant extracts. Background technique [0002] Gastritis is a general term for gastric mucosal inflammation. It is a common disease and can be divided into acute and chronic types. Acute gastritis is common in simple and erosive forms. Gastric ulcer is one of the common and frequently-occurring diseases among the Chinese population. The incidence of gastric ulcer has begun to decline. However, it is still one of the most common diseases in the digestive system. Its occurrence is mainly related to the gastric and duodenal mucosa Damage factors are related to the imbalance between mucosal self-defense and repair factors. Helicobacter pylori infection, non-steroidal anti-inflammatory drugs (NSAIDs, such as aspirin), alcohol consumption, and abnormal gastric acid secretion are common causes of gastric mucosal damage. [0003] At present, the treatmen...

Claims

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Application Information

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IPC IPC(8): A61K31/365A61P1/04A61P31/04
Inventor 刘益明赵韶华卢会芬王猛张晓凤周梦夏
Owner SHIJIAZHUANG YILING PHARMA
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