Traditional Chinese medicament for treating liver-kidney yin deficiency type meniere disease and preparation method thereof

A Meniere's and Yin-deficiency type of technology, applied in the field of pharmacy, can solve the problems of inappropriate or out-of-treatment of purulent ear disease, injury to the orifice, perforation of the membrane and bone decay, etc., to achieve less toxic and side effects, less recurrence, The effect of strict compatibility

Inactive Publication Date: 2014-10-29
QINGDAO BAIHUIZHIYE BIOTECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In addition, if the treatment of purulent ear is not done properly or out of treatment, toxins and evils are eroded, the membranes are penetrated and the bones are rotting, and the orifices are injured, which can also cause ear vertigo.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0067] Wherein, when the dosage form of the Chinese medicine is a honey-refined pill, its preparation method comprises the following steps:

[0068] Step 1: first mix Chinese yam, licorice, Acanthopanax, angelica, rehmannia glutinosa, white peony root and Polygonum multiflorum according to the stated ratio, and distill and crystallize to obtain powder;

[0069] Step 2: Take the remaining raw materials and mix them according to the ratio, add 2-6 times the amount of 83-94% ethanol to soak for 1-2 hours, heat and extract twice, each time for 1-1.5 hours, and combine the extracts , 124-150 mesh filtration, and then ultrafiltration through an ultrafiltration column with a cut-off molecular weight of 4400-98000, and the ultrafiltrate is concentrated under reduced pressure to an extract with a relative density of 1.04 at 87°C, which becomes component 1;

[0070] Step 3: Soak the dregs of the traditional Chinese medicine in step 2 with 4-6 times the amount of water for 1-2.5 hours, h...

Embodiment 1

[0086] Embodiment 1 honey refining pill of the present invention

[0087] Take 20g of yam, 27g of licorice, 25g of Acanthopanax, 22g of Angelica, 13g of Rehmannia glutinosa, 22g of white peony, 33g of Polygonum multiflorum, 40g of dodder, 17g of dog ridge, 8g of ochre, 21g of chrysanthemum seed, 31g of medlar, 14g of dendrobium, sealwort 24g, Eclipta 31g, Ligustrum lucidum 20g, Mulberry 30g, Morinda officinalis 27g, Digupi 15g, Owl 3g, Alisma 43g, Magnolia officinalis 28g, halo medicine 24g, Shayuanzi 35g, Phlox 25g and sage Vegetable 20g. .

[0088] Its preparation method comprises the following steps:

[0089] Step 1: first mix Chinese yam, licorice, Acanthopanax, angelica, rehmannia glutinosa, white peony root and Polygonum multiflorum according to the stated ratio, and distill and crystallize to obtain powder;

[0090] Step 2: Take the remaining raw materials and mix them according to the stated ratio, add 83% ethanol which is twice the amount of the mixture, soak for 2...

Embodiment 2

[0094] Embodiment 2 Tablet of the present invention

[0095] Take 37g of yam, 15g of licorice, 15g of Acanthopanax, 12g of angelica, 23g of Rehmannia glutinosa, 34g of white peony root, 22g of Polygonum multiflorum, 25g of dodder seed, 30g of dog ridge, 19g of ochre, 11g of chrysanthemum seed, 15g of medlar, 23g of dendrobium, sealwort 14g, Eclipta 21g, Ligustrum lucidum 32g, Mulberry 19g, Morinda officinalis 16g, Digupi 26g, Owl 10g, Alisma 29g, Magnolia officinalis 17g, halo medicine 35g, Shayuanzi 27g, Phlox 15g and sage Vegetable 33g.

[0096]The first step is to mix the raw materials of the traditional Chinese medicine in proportion, add ethanol with an alcohol concentration of 90% that is 4 times the mass of the mixture, heat and reflux for 4 hours, extract, and filter to obtain the first extract; filter the obtained dregs Then add ethanol with an alcohol concentration of 90% relative to the quality of the dregs, heat and reflux for 3 hours, extract, and filter to obtai...

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Abstract

The invention discloses a traditional Chinese medicament for treating liver-kidney yin deficiency type meniere disease and a preparation method thereof. The traditional Chinese medicament comprises the following raw medicinal materials: Chinese yam, glycyrrhiza uralensis, acanthopanax root, Chinese angelica, prepared rehmannia root, radix paeoniae alba, polygonum multiflorum, semen cuscutae, rhizoma cibotii, red ocher, fructus broussonetiae, fructus lycii, dendrobe, rhizoma polygonati, herba ecliptae, glossy privet fruit, mulberry, morinda officinalis, cortex lycii radicis, owl, rhizoma alismatis, magnolia officinalis, polygonum chinense, semen astragali complanati, rubus hirsutus and Indian rorippa herb. The traditional Chinese medicament is mainly used for nourishing liver and kidney, nourishing yin and replenishing essence by utilizing the traditional Chinese medical theory, is prepared from traditional Chinese medicinal materials with different properties, mild drug effect and strict compatibility for treating liver-kidney yin deficiency type meniere disease, performs treatment based on syndrome differentiation from the overall aspect, and has the beneficial effects that the drug effect can directly reaches a focus, the curing time is short, the disease cannot easily relapse after being healed, the toxic and side effects are small, the taste is appropriate and easily accepted by patients, the preparation process is simple and convenient, and the preparation is easy to manufacture at low cost.

Description

technical field [0001] The invention relates to the technical field of pharmacy, in particular to a traditional Chinese medicine for treating Meniere's syndrome of liver-kidney yin deficiency type and a preparation method thereof. [0002] Background technique [0003] Meniere's syndrome is Meniere's disease. Ménières disease (Ménières disease) is an idiopathic inner ear disease first proposed by French physician Prosper Ménière in 1861. The main pathological change of the disease is membranous labyrinth hydrops, and the clinical manifestations are recurrent rotational vertigo, fluctuating hearing loss, tinnitus and ear fullness. The disease mostly occurs in middle-aged and young people aged 30 to 50, and it is rare in children. There was no significant difference in the incidence of men and women. About 10% to 50% of patients with binaural disease. [0004] The etiology of Meniere's disease is still unclear. In 1938, Hallpike and Cairns reported that the main patholog...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8984A61P1/08A61P27/16A61K33/26A61K35/12A61K9/20A61K9/48
Inventor 崔亮亮张瑞丽王春元
Owner QINGDAO BAIHUIZHIYE BIOTECH
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