Gout-resisting pharmaceutical composition and preparation method of gout-resisting pharmaceutical composition

A composition and anti-gout technology, applied in the direction of drug combination, pharmaceutical formula, drug delivery, etc., can solve the problems of inappropriate aspirin combined use, allergic damage to liver and kidney function, gastrointestinal side effects, etc., without obvious adverse effects Response, no complications, effect of relieving patients' pain

Active Publication Date: 2015-01-07
蚌埠丰原涂山制药有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] At present, modern anti-gout drugs mostly rely on colchicine, allopurinol, anti-inflammatory drugs, etc. to inhibit uric acid synthesis and relieve symptoms. The disadvantages are: 1. Short-term curative effect, but long-term curative effect is not ideal, high cost, large toxic and side effects, Cannot continue treatment
2. Long-term application of colchicine can cause bone marrow suppression, damage to liver, kidney, and heart function, and gastrointestinal side effects. Intravenous injection can easily cause local phlebitis
3. Allopurinol is allergic, damages liver and kidney function, in...

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0033] Embodiment 1 anti-gout pharmaceutical composition and preparation method thereof

[0034] 1. Raw materials:

[0035] Table 1 anti-gout pharmaceutical composition raw material formula

[0036] Chinese herbal medicine

Weight (kg)

weight percentage (%)

Clematis

110

18.0

Xu Changqing

100

16.4

Notopterygium

65

10.7

live alone

65

10.7

herb

80

13.1

Achyranthes knee

80

13.1

Astragalus

110

18.0

total

610

100

[0037] 2. Preparation method:

[0038] 1) Weigh the above seven herbs according to the formula in Table 1.

[0039] 2) Soak Notopterygium, Duhuo, Xu Changqing, and Atractylodes in water with 6 times the weight of medicinal materials, soak for 8 hours, and extract the volatile oil by steam distillation. The extraction time is 4 hours. The distilled aqueous solution is collected in a separate container, and the residue is recovere...

Embodiment 2

[0043] Embodiment 2 anti-gout pharmaceutical composition and preparation method thereof

[0044] 1. Raw materials:

[0045] Table 2 anti-gout pharmaceutical composition raw material formula

[0046] Chinese herbal medicine

Weight (kg)

weight percentage (%)

Clematis

88

15.0

Xu Changqing

120

20.5

Notopterygium

52

8.9

live alone

78

13.3

herb

64

10.9

Achyranthes knee

96

16.4

Astragalus

88

15.0

total

586

100

[0047] 2. Preparation method:

[0048] 1) Weigh the above seven herbs according to the formula in Table 2.

[0049] 2) Soak Notopterygium, Duhuo, Xu Changqing, and Atractylodes in water with 7 times the weight of medicinal materials, soak for 6 hours, extract the volatile oil by steam distillation for 5 hours, collect the distilled aqueous solution in a separate container, recover the residue, and store the volatile oil in a separa...

Embodiment 3

[0053] Embodiment 3 anti-gout pharmaceutical composition and preparation method thereof

[0054] 1. Raw materials:

[0055] Table 3 anti-gout pharmaceutical composition raw material formula

[0056] Chinese herbal medicine

Weight (kg)

weight percentage (%)

Clematis

132

20.8

Xu Changqing

80

12.6

Notopterygium

78

12.3

live alone

52

8.2

herb

96

15.1

Achyranthes knee

64

10.1

Astragalus

132

20.8

total

634

100

[0057] 2. Preparation method:

[0058] 1) Weigh the above seven herbs according to the formula in Table 3.

[0059] 2) Soak Notopterygium, Duhuo, Xu Changqing, and Atractylodes in water with 8 times the weight of medicinal materials, soak for 7 hours, extract the volatile oil by steam distillation, the extraction time is 3 hours, collect the distilled aqueous solution in a separate device, recover the residue, and store the volati...

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PUM

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Abstract

The invention provides a gout-resisting pharmaceutical composition and a preparation method of the gout-resisting pharmaceutical composition. The gout-resisting pharmaceutical composition comprises radix clematidis, notopterygium roots, radix angelicae pubescentis, cynanchum paniculatum, rhizoma atractylodis, radix achyranthis bidentatae and astragalus membranaceus. The gout-resisting pharmaceutical composition is accurate in curative effect, low in cost, low in contraindication and low in untoward effect, and provides a selection of gout treating medicines for patients.

Description

technical field [0001] The invention relates to a pharmaceutical composition and a preparation method thereof, in particular to an anti-gout pharmaceutical composition and a preparation method thereof. Background technique [0002] Gout is similar to traditional Chinese medicine "calendar festival", "beriberi", "gout" and "phlegm-fire poison". Because it travels and injects joints, the pain is very severe, so it is also called "white tiger calendar festival". It is generally believed that there is heat in one's own blood, and poison accumulates in the viscera, and the dampness and heat are accumulated in the body after overeating the thick taste of sorghum. Gout belongs to the category of "arthralgia syndrome" in traditional Chinese medicine. Its etiology and pathogenesis are insufficient congenital endowment, weak righteousness, weak external defense, easy to be attacked by wind, cold, damp and heat, leaving joints and muscles, causing meridian blockage; Indulging in fat, ...

Claims

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Application Information

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IPC IPC(8): A61K36/716A61P19/06A61P13/04
CPCA61K9/08A61K9/14A61K9/16A61K9/20A61K9/48A61K36/21A61K36/232A61K36/237A61K36/27A61K36/284A61K36/481A61K36/716A61K2236/331A61K2236/51A61K2236/53A61K2300/00
Inventor 马其胜陈华彪尹群孙鹏何莹莹李保琴李成名
Owner 蚌埠丰原涂山制药有限公司
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