The invention relates to an external used medicine prepared based on traditional Chinese medicines for treating tumor, wherein powder product is prepared by taking gecko, nidus vespae, cynanchum paniculatum, astragalus mongholicus, codonopsis pilosula, rhizoma atractylodis alba, hairyvein agrimony, semen coicis, safflower carthamus, amethyst, manyleaf paris rhizome, honey-fried licorice root, toad skin, stiff silkworm, pillis ophidiae, zaocys dhumnade, agkistrodon, rhizoma corydalis, angelica sinensis, cortex albiziae, Flos Albiziae, scorpio, centipede, lumbricus, polygala tenuifolia, amber, chlorite schist, leech, gadfly, ground beeltle, manis pentadactyla, and oldenlandia diffusa, which are finely selected and cleaned with clear water, mixing uniformly, crushing to 60-80 meshes medicine powders, and sterilizing. The medicine has functions in combating poison with poison, dispelling wind and removing obstruction in the meridians, clearing away heat and toxic materials, promoting blood circulation to remove blood stasis, smoothing the nerves, combating poison, removing stasis, tonifying Qi and strengthening healthy energy, can inhibit and kill tumor cells effectively, and has significant treating effect to tumors without toxic and side effects.