Akermanite/PMMA composite bone cement with osteogenesis inducing function and preparation method of akermanite/PMMA composite bone cement

A technology of magnesia feldspar and bone cement, which is applied in surgical adhesives, medical science, surgery, etc., to achieve the effect of improving biological activity and biocompatibility, wide application, and good mechanical properties

Active Publication Date: 2015-01-28
SHANGHAI INST OF CERAMIC CHEM & TECH CHINESE ACAD OF SCI
View PDF4 Cites 15 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

PMMA bone cement with the function of actively inducing osteogenesis has not been reported yet

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Akermanite/PMMA composite bone cement with osteogenesis inducing function and preparation method of akermanite/PMMA composite bone cement
  • Akermanite/PMMA composite bone cement with osteogenesis inducing function and preparation method of akermanite/PMMA composite bone cement
  • Akermanite/PMMA composite bone cement with osteogenesis inducing function and preparation method of akermanite/PMMA composite bone cement

Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0028] The preparation method of the described magnesia feldspar / PMMA composite bone cement with the function of inducing osteogenesis comprises the following steps:

[0029] (1) The feldspar powder was prepared by sol-gel method. Tetraethyl orthosilicate was mixed with deionized water and 2mol·L -1 Nitric acid mixed and hydrolyzed with stirring for half an hour. Then, calcium nitrate and magnesium nitrate were sequentially added into the mixed solution according to the metering ratio, and a clear solution was obtained after stirring for 5 hours, then sealed in an oven at 60°C for 24 hours and dried at 120°C for 48 hours to obtain a xerogel. Ball mill the xerogel and pass through a 120-mesh sieve, and finally calcinate at 1300°C for 3 hours, and cool naturally to obtain feldspar powder;

[0030] (2) sieve the feldspar powder obtained in step (1), uniformly mix the feldspar and PMMA powder of 5-60% by mass ratio, and then according to the ratio of bone cement monomer and PMMA...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

PropertyMeasurementUnit
solidification timeaaaaaaaaaa
particle diameteraaaaaaaaaa
Login to view more

Abstract

The invention discloses akermanite / PMMA composite bone cement with an osteogenesis inducing function and a preparation method of the akermanite / PMMA composite bone cement. The akermanite / PMMA composite bone cement comprises the following components: akermanite and PMMA bone cement, wherein the PMMA bone cement is prepared from a PMMA bone cement monomer and PMMA powder, and the mass ratio of the akermanite to PMMA powder is 5-60 percent.

Description

technical field [0001] The invention relates to a magnesian feldspar / PMMA composite bone cement with the function of inducing osteogenesis and a preparation method thereof, belonging to the field of biological materials. Background technique [0002] As a kind of bone repair material, polymethacrylic acid bone cement (PMMA bone cement) has become an important material for fixing artificial joints, connecting hosts and prostheses since the 1960s, and is widely used in bone defects. fractures and dental restorations. If used correctly, PMMA bone cement can achieve good surgical results (approximately 90% of joint replacement operations can last more than 10 years). But there are many defects in traditional PMMA bone cement [P.Liu-Snyder, T.J.Webster, Developing a new generation of bone cements with nanotechnology, Current Nanoscience 4 (1) (2008) 111-118]: (1) lack of PMMA bone cement Interface activity, unable to form a stable and firm interface between the bone and the imp...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
Patent Type & Authority Applications(China)
IPC IPC(8): A61L24/06A61L24/02A61L27/16A61L27/10A61L27/54
Inventor 常江陈蕾
Owner SHANGHAI INST OF CERAMIC CHEM & TECH CHINESE ACAD OF SCI
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap