Limb local drug delivery and dialysis device and application thereof

A local drug delivery and dialysis device technology, applied in dialysis systems, semi-permeable membrane separation, drug devices, etc., can solve problems such as the impact of anti-tumor drugs on normal tissues

Active Publication Date: 2015-01-28
SHANGHAI SIXTH PEOPLES HOSPITAL
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0005] In the clinical treatment of patients with limb malignant tumors, systemic chemotherapy with antineoplastic drugs is often performed before amputation or prosthetic limb salvage to avoid o...

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  • Limb local drug delivery and dialysis device and application thereof

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Embodiment Construction

[0021] The embodiments of the present invention are described in detail below. This embodiment is implemented on the premise of the technical solution of the present invention, and detailed implementation methods and specific operating procedures are provided, but the protection scope of the present invention is not limited to the following implementation example.

[0022] Such as figure 1 As shown, this embodiment includes an arterial chamber 1 and a venous chamber 2; the arterial chamber 1 and the venous chamber 2 are two mutually isolated boxes, and the arterial chamber 1 is provided with a An arterial blood inlet 11, an arterial blood outlet 12 matched with the other end of the aorta and a drug administration inlet 13, the arterial blood inlet 11 is located at the top of the arterial chamber cavity 1, and the arterial blood outlet 12 is located at the bottom of the arterial chamber chamber 1, giving The medicine inlet 13 is located between the arterial blood inlet 11 and ...

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Abstract

The invention discloses a limb local drug delivery and dialysis device and an application thereof. The limb local drug delivery and dialysis device is characterized in that an arterial blood inlet, an arterial blood outlet and at least one drug delivery inlet are arranged on an arterial chamber, wherein the arterial blood inlet is matched with one end of a main artery, and the arterial blood outlet is matched with the other end of the main artery. A venous blood inlet, a venous blood outlet, a dialysate inlet and a dialysate outlet are arranged on a venous chamber, wherein the venous blood inlet is matched with the limb side of the vein, and the venous blood outlet is matched with the proximal side of the vein. A blood coil of a dialysing tube structure is arranged in the venous chamber, one end of the blood coil is connected with the venous blood inlet, and the other end of the blood coil is connected with the venous blood outlet. The limb local drug delivery and dialysis device filter backflow venous blood molecules with specific sizes while performing arterial drug delivery, provides drugs for limbs on the affected side, and limits the drugs to the blood circulation in the affected limbs; discharges harmful substances generated by the affected limbs and prevents the harmful substances from entering whole-body blood circulation, thereby achieving the purpose of treating localized lesions of the limbs.

Description

technical field [0001] The invention relates to a medical auxiliary product, in particular to a local drug delivery and dialysis device for extremities and its application. Background technique [0002] With the frequent occurrence of earthquakes, traffic accidents, landslides, etc., more and more patients with limb crush injuries and severed injuries; Symptoms and other side effects can be life-threatening. For other patients, such as diabetic foot, malignant tumors with localized limbs, osteomyelitis, etc., the drug concentration in the lesion area is too low to achieve the best effect through intravenous administration, and the systemic drug concentration is too high. influences. If the patient's limbs are squeezed for too long (at room temperature, more than 6 to 7 hours), it can cause muscle cell degeneration and necrosis, and release a large amount of myoglobin, potassium ions, magnesium ions, phosphate, sulfate, and non-protein nitrogen; and After the weight is rem...

Claims

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Application Information

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IPC IPC(8): A61M1/16
CPCA61M1/16A61M2202/0007A61M2202/0413A61M2205/05A61M2210/005B01D69/043
Inventor 张长青于晓巍
Owner SHANGHAI SIXTH PEOPLES HOSPITAL
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