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Biosensor and preparation method thereof

A biosensor and sensor technology, applied in the field of biosensors, can solve the problems of high overall cost of sensors, difficult to popularize and use sensors, expensive silicon wafers, etc., and achieve the effects of low cost, low price and simple process

Inactive Publication Date: 2015-03-11
赵天贤
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The accuracy of the sensor prepared by the above method is very good, but because the silicon wafer is more expensive, and there are more precious metals such as gold and platinum wasted in the production process, the overall cost of the sensor is relatively high, and the sensor is difficult to popularize and use

Method used

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  • Biosensor and preparation method thereof

Examples

Experimental program
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Effect test

Embodiment 1

[0039] see Figure 1 to Figure 3 , using the preparation method of the biosensor of the present invention to make the steps of the current-type electrochemical sensor base plate is:

[0040] 1) Select a common PCB raw material board as the substrate board, the insulating substrate 12 of the PCB raw material board can be bakelite board, paper resin board, glass resin board, ceramic material board, etc., and the conductive layer 13 is generally copper foil;

[0041] 2) Through the standard PCB chemical etching process, the excess copper foil is removed, and the rest are the required conductive parts, including common conductive parts, reaction electrode substrates for electrochemical reactions, and retaining rings for placing reagents 19 And heating resistance 20; Wherein, common conductive part comprises the conductive plate 14 that is used to connect sensor and analyzer, lead 15 and is used for monitoring the electrode 16 that sample joins; Except two reaction electrodes 17,18...

Embodiment 2

[0047] see Figure 4 , utilize the preparation method of biosensor of the present invention to make the step of voltage-type electrochemical sensor bottom plate as follows:

[0048] 1) select the common PCB raw material plate identical with embodiment 1 as matrix plate;

[0049] 2) Through the standard PCB chemical etching process, the excess copper foil is removed, and the rest are the required conductive parts, including common conductive parts, reaction electrode substrates for electrochemical reactions, and retaining rings for placing reagents 19 And heating resistance (same as embodiment 1, figure not shown); Wherein, common conductive part comprises the conductive plate 14 that is used to connect sensor and analyzer, lead 15 and is used to monitor the electrode 34 that sample adds; Except three reaction electrodes Except for 31, 32 and 33, other conductive parts have been made through this step;

[0050] 3) Cover silver / silver chloride on the base copper of the three r...

Embodiment 3

[0054] see Figure 5 , using the preparation method of the biosensor of the present invention to make the impedance biosensor base plate steps are:

[0055] 1) select the common PCB raw material plate identical with embodiment 1 as matrix plate;

[0056] 2) By standard PCB chemical etching process, the excess copper foil is removed, and the remaining is the required conductive parts, including common conductive parts, reaction electrode substrates and heating resistors for electrochemical reactions (similar to Example 1 same, not shown in the figure); wherein, the common conductive parts include conductive plates 14 and wires 15 for connecting sensors and analyzers; except four electrodes 41, 42, 43, 44, other conductive parts have been made through this step become;

[0057] 3) Cover silver / silver chloride onto the base copper of the four electrodes 41, 42, 43, 44 by standard electroplating or chemical methods to obtain two electrodes 41, 44 for applying current and two ele...

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Abstract

The invention discloses a biosensor and its preparation method. The preparation method comprises the following steps: 1) a PCB, a raw material plate is used as a substrate panel, and an insulated substrate and a conductive part of the biosensor are manufactured by a PCB manufacturing technology, wherein the conductive part contains various wires and electrodes; 2) different electrodes of the conductive part are coated with different electrode materials by an electroplating method or a chemical method to prepare various special electrodes required by the biosensor, and baseboard of the biosensor is obtained; and 3) the baseboard prepared in the step 2) is used to prepare the biosensor provided by the invention. In comparison with the prior art, the baseboard of the biosensor provided by the invention is prepared by the PCB technology, and the biosensor provided by the invention has advantages of simple technology and low cost. Thus, high performance and low cost can be achieved. The biosensor is especially suitable for instant detection of various biological signals such as various blood parameters (blood clotting,blood sugar, cardiac troponin and the like), contagious virus (tuberculosis, hepatitis B, HIV, etc.) and the like.

Description

technical field [0001] The invention belongs to the field of biosensors, more specifically, the invention relates to a high-performance and low-cost biosensor manufactured by a printed circuit board (PCB) process and a preparation method thereof. Background technique [0002] With the development of various technologies, biosensors and corresponding detection instruments can become smaller and smaller, so that point-of-care detection (POCT) in clinical medicine has become possible and developed rapidly. [0003] The main advantage of POCT is that the test results can be obtained within a few minutes, so medical staff can directly detect the patients around them and diagnose and treat diseases based on the test results, without the need to send samples to Central laboratory, waiting for the results to follow up; this is obviously very useful in the medical field where "time is of the essence". For example, when a patient with chest discomfort is received in the emergency dep...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N33/50
CPCG01N33/50G01N27/02G01N27/26
Inventor 赵天贤
Owner 赵天贤