A kind of Gezao kiwifruit effervescent agent and its preparation method and application
A technology of kudzu kiwi fruit and effervescent agent, which is applied in the directions of antidote, pharmaceutical formulations, medical preparations with non-active ingredients, etc., can solve the problems of inability to supply the fruit to the market, short storage time, sour taste, etc.
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Embodiment 1
[0080] Example 1 Preparation of fruit juice inclusion compound, extraction of active ingredients in pomace and preparation of effervescent agent, capsule and effervescent tablet
[0081] 1) Preparation of fruit juice inclusion complex: Wash and select the Actinidia kudzu fruit, and add citric acid to the Actinidia kudzu fruit for soaking treatment. The soaking time is 8 minutes, and the amount of citric acid added is 0.25% of the mass of the Actinidia kudzu fruit. , add the 2% liquid nitrogen of described kudzu jujube kiwifruit quality, utilize LE-2 screw juice extractor to extract juice quickly, collect juice, add polysorbate 80 and sodium sulfite (purpose is to prevent vitamin C from degrading) successively in juice, make it The concentration is 0.02mg / ml, and nitrogen gas is passed through at a nitrogen rate of 15ml / min. 25U of pectinase is added to each gram of the fruit juice, and the enzyme is hydrolyzed at 36°C for 1.5h to detect and control Vc degradation. And in descr...
Embodiment 2
[0102] Embodiment 2: Gezizao kiwifruit preparation and active polysaccharide component Rz 1-3 Hypoglycemic and anti-fatigue studies
[0103] The weight-bearing model of mice (Kunming species) was used for research, and the anti-fatigue activity was studied by using the swimming time and the content of whole blood lactic acid as indicators; the STZ-induced type 2 diabetic mice were used as models to study its hypoglycemic effect. The results are shown in Table 1 and Table 2:
[0104] Table 1 Effects of active polysaccharides and their preparations on the swimming time of Kunming mice
[0105] group
Number of animals (only)
Dosage (mg kg -1 d -1 )
Swimming time (min)
NC (blank)
10
0
152.2
Rz 1
10
100
161.1
Rz 1
10
200
178.5
Rz 1
10
300
192.6
Rz 2
10
100
172.4
Rz 2
10
200
199
Rz 2
10
300
201.7
Rz 3
...
Embodiment 3
[0111] Embodiment 3: active polysaccharide component Rz 1-3 Effect of Gezao and kiwifruit preparation on hypoglycemic effect in type 2 diabetic mice
[0112] Control group mice: select 100 healthy Kunming mice weighing about 20 g, and after one week of adaptive feeding, give intraperitoneal injection of sodium citrate buffer solution with a concentration of 5 mg / ml every morning, and inject 35 mg / kg per day according to body weight, continuously Three days after the injection, the mice drank tap water and fed with conventional mouse feed.
[0113] Experimental group of mice: select 100 healthy Kunming mice with a body weight of about 20 g, and after adaptive feeding for one week, give STZ solution (streptozotocin solution) with a concentration of 5 mg / ml intraperitoneally every morning. Inject 35 mg / kg for 3 consecutive days. Mice drink tap water and feed with mouse high-fat and high-sugar diet.
[0114] Observe the drinking and eating situation every day, check the body wei...
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