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A kind of medical organosilicon pancreatic-intestinal stapler material and preparation method thereof

A technology of silicon pancreatojejunostomy and stapler is applied in the field of medical organic silicon pancreatojejunostomy material and its preparation, which can solve the problems of difficult operation, easy occurrence of pancreatic fistula and the like

Inactive Publication Date: 2017-04-19
XIAN UNIV OF SCI & TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0005] One of the purposes of the present invention is to provide a medical organosilicon pancreatic-intestinal stapler material with high elasticity and tear resistance in order to overcome the medical difficulty of pancreaticojejunostomy in patients with pancreatic cancer and the postoperative pancreatic fistula.

Method used

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  • A kind of medical organosilicon pancreatic-intestinal stapler material and preparation method thereof
  • A kind of medical organosilicon pancreatic-intestinal stapler material and preparation method thereof
  • A kind of medical organosilicon pancreatic-intestinal stapler material and preparation method thereof

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preparation example Construction

[0046] The preparation method of the medical organosilicon pancreatic-intestinal stapler material of the present invention comprises the following steps:

[0047] (1) After mixing the modifier with a mass ratio of 1:1 with absolute ethanol, add it into the flask together with the reinforcing agent, stir evenly in a water bath at 70-80°C, take it out, and dry it in a vacuum oven ;

[0048] Among them, the modified reinforcing agent is ultrafine mineral powder, fumed white carbon black or nano-calcium carbonate powder after the modifier is mixed with absolute ethanol and dried; the modifier is the silane coupling agent KH- 550 (γ-aminopropyltriethoxysilane) or hydroxyl-terminated linear polydimethylsiloxane.

[0049] (2) Add 10-30% of the modified reinforcing agent and 3-5% of the structure control agent into the 60-80% of the silicone rubber matrix for mixing, and then add 2-4% of the vulcanizing agent, 0.5-1.5% of the The joint agent is mixed evenly, and the mixing time and ...

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Abstract

The invention discloses a medical organosilicon pancreatic-intestinal stapler material and a preparation method thereof. The material comprises: 60-80% of a silicone rubber matrix; 3-5% of a structure control agent; 2-4% of a vulcanizing agent; 0.5-80% of a vulcanizing agent 1.5% crosslinker; 0.05‑0.1% catalyst; 10‑30% reinforcing agent. The method includes: (1) preparation of masterbatch; (2) mixing; (3) parking of the mixed rubber; (4) two-stage vulcanization; (5) post-treatment after gradually raising the temperature to obtain the medical organic silicon elastomer pancreatic-intestinal stapler material. It also includes a pancreas-intestine stapler made of medical organic silicon elastomer material, the stapler is strip-shaped, and titanium nails are evenly distributed on it. The medical silicone elastomer material is an elastomer material with high ductility and high tear strength. It has the characteristics of physiological non-toxicity, high flexibility, high ductility and excellent medium resistance, and can be widely used in medicine. field.

Description

technical field [0001] The invention relates to a medical organosilicon elastomer pancreatic-intestinal stapler material, in particular to a medical organosilicon pancreatic-intestinal stapler material with better elasticity and excellent mechanical properties and a preparation method thereof. Background technique [0002] Since Wipple pioneered pancreaticoduodenectomy in 1935, after nearly 80 years of development, there have been more than 50 pancreaticojejunostomy methods recorded in the literature. Clinically, the following three methods of pancreaticojejunostomy are mainly used: sleeve-type end-to-end pancreaticojejunostomy, pancreatic duct-to-mucosal end-to-side pancreaticojejunostomy, and bundled pancreaticojejunostomy. [0003] Bundled pancreaticojejunostomy is an end-to-end sleeve-type anastomosis, which is an improved anastomosis method, but the actual operation is quite troublesome, and when the anastomotic site is tied up with a thick thread at the end, the pancre...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61L31/06A61L31/02B29C35/02B29C71/00
Inventor 李颖
Owner XIAN UNIV OF SCI & TECH
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