Method for preparation of Rosavin from Rhodiola rosea L.

Abstract

The invention discloses a method for preparation of Rosavin from Rhodiola rosea L. The method comprises the steps of: (1) subjecting Rhodiola rosea L. to coarse grinding, putting the ground Rhodiola rosea L. into a 80% methanol water solution, conducting heating reflux for 2h, then releasing an extracted solution, adding the methanol water solution again, conducting heating reflux for 1h, and then releasing the extracted solution again; (2) combining the two collected extracted solutions, placing the combined solution into a vacuum concentrator to carry out distillation to recover methanol, thus obtaining a viscous concentrated solution; (3) adding water that is 5 times the volume of the concentrated solution and stirring the mixture evenly, then performing standing layering, removing the precipitate, and taking the supernatant; (4) subjecting the supernatant to macroporous resin adsorption, firstly conducting flushing with water till the effluent liquid is transparent and colorless, and then employing methanol with a concentration of more than 70% to elute macroporous resin, thus obtaining an eluent; (5) distilling the eluent to recover methanol, and further evaporating water to a Baume degree of 18; and (6) carrying out spray drying, thus obtaining a light yellow powder product.

Description

technical field [0001] The invention relates to a method for extracting Chinese herbal medicines, in particular to a method for preparing rosavir from rhodiola rosea. Background technique [0002] There are more than 200 species of rhodiola, which grow in cold and arid plateau areas. They are rare plants with strong vitality and special adaptability. [0003] At present, there are only two species of Rhodiola rosea produced in Xinjiang and Central Asia and Rhodiola daflora produced in Tibet that have industrial extraction value. Among them, Rhodiola grandiflora only contains salidroside, while Rhodiola rosea contains all the iconic components of Rhodiola rosea: rosevi (the most active), luosai, rosailin, and salidroside. [0004] Rhodiola rosea, also known as Rhodiola rosea, is famous for its effects of eliminating fatigue, anti-hypoxia, anti-depression, anti-radiation and delaying aging. In recent years, the extract of Rhodiola rosea (salidroside content 1%-3%) has entere...

AI Technical Summary

Problems solved by technology

At present, there are not many methods for preparing rosevin from Rhodiola rosea in Chinese manufacturers, and the preparation is cumbersome and wasteful. For example, in a preparation method of rosavir in the patent No. 201110026194.9, the extraction solvent is ethanol, and the cost is high. A variety of materials are used in the process: ethyl acetate, polyamide resin, alumina column, ether, etc., which increase the preparation cost, and the steps are cumbersome and troublesome to operate. Therefore, in order to reduce the production cost and thereby reduce the price, so that our citizens can consume this As soon as a product is produced, it is necessary to develop a convenient, simple, large-quantity, and low-cost preparation method for rosevin