Tissue vascular clamp capable of being decomposed by body fluid

A blood vessel clip and tissue technology, applied in the field of medical metal clips, can solve the problems of broken clips, easy to fall off, and weak clipping ability, and achieve the effect of strong clipping ability, not easy to fall off, and small tissue reaction

Inactive Publication Date: 2015-04-15
SHANGHAI NINTH PEOPLES HOSPITAL AFFILIATED TO SHANGHAI JIAO TONG UNIV SCHOOL OF MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Absorbable vascular closure clips from Johnson & Johnson tend to soften rapidly when exposed to water (including blood, body cavity fluid, etc.), and the clamping force is not strong
The absorbable blood vessel closure clip produced by Tyco Company of the United States will squeeze the tissue outward when the clip is completely closed, r...

Method used

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  • Tissue vascular clamp capable of being decomposed by body fluid

Examples

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Comparison scheme
Effect test

Embodiment 1

[0028] This embodiment provides a body fluid-degradable tissue blood vessel clip, the tissue blood vessel clip is composed of pure magnesium, including a mother arm 1, a self-locking arm 2 and a child arm 3, one end of the mother arm 1 is connected to one end of the child arm 3, A V-shaped or U-shaped structure is formed; the other end of the female arm 1 is connected to the self-locking arm 2, and the angle w between the self-locking arm 2 and the female arm 1 is 92°.

[0029] The length of the child arm 3 is greater than that of the mother arm 1 . The lower surface of the self-locking arm 2 is provided with a plurality of racks 21 parallel to each other, an acute angle θ is formed between each rack 21 and the lower surface of the self-locking arm 2, and the acute angle θ faces the other end of the self-locking arm 2; The other end of the sub-arm 3 forms an acute angle α, and the acute angle α deviates from the mother arm 1. The acute-angled end of the sub-arm 3 can be insert...

Embodiment 2

[0033] The body fluid-degradable tissue and blood vessel clip provided in this embodiment is different from the embodiment in that the tissue and blood vessel clip is made of AZ31 magnesium alloy.

[0034] Biological safety: carry out biological evaluation according to the experimental method described in GB / T16886. The experimental results show that the material of this example has no obvious cytotoxicity and coagulation property to epithelial cells, fibroblasts and smooth muscle cells, and has no obvious sensitization, stimulation and genotoxicity.

[0035] In vivo test and degradation test: 5 New Zealand rabbits were taken, laparotomed, 10 tissues were randomly selected for clipping, sutured, and after 3 months of feeding, it was found that the magnesium alloy was degraded by 40%, and there was no inflammatory reaction, no adhesion, and no shedding at the clamped place .

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Abstract

The invention provides a tissue vascular clamp capable of being decomposed by body fluid. The tissue vascular clamp is made from magnesium-based metal, consists of a primary arm, a self-locking arm, a secondary arm, wherein one end of the primary arm is connected with one end of the secondary arm to form a V-shaped or U-shaped structure; one end of the primary arm is connected with the self-locking arm with an included angle w larger than 80 degrees and smaller than 110 degrees; self-locking devices which are matched with one another are arranged at the other ends of the self-locking arm and the secondary arm. The tissue vascular clamp capable of being decomposed by body fluid provided by the invention is strong in clamping capacity, not prone to drop, can be completely degraded in the body to release trace elements and locally antibacterial, is small in tissue reaction, and does not cause tissue adhesion or obstruction.

Description

technical field [0001] The invention relates to a medical metal clip, in particular to a body fluid-degradable tissue blood vessel clip used in surgery. Background technique [0002] In the prior art, metal titanium clips, usually U-shaped titanium clips, are still the most used in the ligation and closure of surgical blood vessels, other blood vessels, and tissues. In clinical use, use special surgical forceps to insert the titanium clip into the jaws of the surgical forceps, and then release it, that is, clamp the jaws of the surgical forceps, and then withdraw from the surgical forceps. The U-shaped titanium clip will tighten the tissue to be closed. Clamp together. This titanium clip has been widely used clinically because of its simple use and definite curative effect. However, in some cases, after the U-shaped titanium center is deformed, under the action of the elastic recovery force of the clamped tissue, slippage occurs, which not only fails to close the clamped t...

Claims

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Application Information

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IPC IPC(8): A61B17/122A61L31/02A61L31/14A61L31/10A61L31/08A61L31/16
CPCA61B17/122A61L31/022A61L31/086A61L31/10A61L31/148A61L31/16A61L2300/252A61L2300/404A61L2300/414A61L2300/604
Inventor 戴尅戎曲新华
Owner SHANGHAI NINTH PEOPLES HOSPITAL AFFILIATED TO SHANGHAI JIAO TONG UNIV SCHOOL OF MEDICINE
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