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Enzyme compounded preparation and preparation method thereof

An enzyme compound preparation, lysostaphin technology, which is applied in the direction of pharmaceutical formulations, medical preparations containing active ingredients, peptide/protein components, etc., can solve the problem of changing the ecological status of normal bacteria in patients, ineffective curative effect, and pathogenic bacteria Infection and other problems, to achieve the effect of inhibiting the reproduction of pathogens, long antibacterial time, and stable antibacterial performance

Inactive Publication Date: 2015-04-22
杨陈
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

At present, clinical bacterial infections are relatively serious, and these bacteria have seriously affected people's health and life. Therefore, a disinfectant that can eliminate bacteria is an urgently needed drug in clinical practice.
[0003] At present, the bacteria that mainly affect life clinically include: Staphylococcus aureus, pneumococcus, Pseudomonas aeruginosa, Candida albicans, Escherichia coli, etc. The infection caused by these bacteria is not curative with conventional treatment methods, and will change The ecological status of the patient's normal flora, causing additional suffering and financial burden to the patient

Method used

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  • Enzyme compounded preparation and preparation method thereof

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Embodiment Construction

[0024] The present invention will be further described in detail below in conjunction with specific embodiments.

[0025] 1. Specific examples

[0026] A lysostaphin compound enzyme disinfection gel, comprising the following components in parts by mass: an enzyme compound preparation, comprising the following components in parts by mass: 0.0005-1 part of lysostaphin enzyme, 0.0025-1 part of antibacterial peptide 0.08-1 part of chlorhexidine acetate, 1-5 parts of sorbitol, 0.01-1 part of sodium dihydrogen phosphate, 0.04-1 part of disodium hydrogen phosphate, 0.2-1 part of essence and 80-100 parts of distilled water. As shown in Table 1, wherein 1#~3# enzyme compound preparations are obtained by adopting the technical scheme of the present invention, 4#~6# are comparative examples, and the composition ratios in each embodiment are shown in Table 1.

[0027] Table 1

[0028] components 1# 2# 3# 4# 5# 6# Lysostaphin 0.0005 0.5964 1 0.5964 0 0.5964 ...

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Abstract

The invention discloses an enzyme compounded preparation, which comprises the following components in parts by mass: 0.0005-1 part of lysostaphin, 0.0025-1 part of antibacterial peptides, 0.08-1 part of chlorhexidine acetate, 1-5 parts of sorbitol, 0.01-1 part of sodium dihydrogen phosphate, 0.04-1 part of disodium hydrogen phosphate, 0.2-1 part of essence, and 80-100 parts of distilled water. The enzyme compounded preparation prepared according to the invention has a wide anti-pathogenic-bacteria spectrum, and has the advantages of high sterilization efficiency, wide sterilization spectrum, and small toxic and side effects. The invention discloses a preparation method of the enzyme compounded preparation, which has the advantages of simplicity in operation, and capability of being subjected to large-scale production.

Description

technical field [0001] The invention relates to the field of disinfectants, in particular to an enzyme compound preparation. Background technique [0002] With the improvement of people's living standards, the requirements for physical health and personal hygiene are also getting higher and higher. At present, the clinical bacterial infection is more serious, and these bacteria have constituted a serious impact on people's health and life, so a disinfectant that can eliminate bacteria is a clinically urgently needed medicine. [0003] At present, the bacteria that mainly affect life clinically include: Staphylococcus aureus, pneumococcus, Pseudomonas aeruginosa, Candida albicans, Escherichia coli, etc. The infection caused by these bacteria is not curative with conventional treatment methods, and will change The ecological status of the normal bacterial species of the patient causes additional suffering and economic burden to the patient. Therefore, it is a clinical probl...

Claims

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Application Information

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IPC IPC(8): A61K38/51A61K47/26A61K47/02A61P31/04A61K31/155A61K38/00
Inventor 杨陈
Owner 杨陈