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Traditional Chinese medicine for treating chloasma and application thereof

A technology of chloasma and traditional Chinese medicine, which is applied in the field of traditional Chinese medicine, can solve problems such as the inability to eradicate chloasma, achieve high cure rate, significant effect, and no toxic and side effects

Inactive Publication Date: 2015-04-29
崔合芳
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Western medicine for the treatment of chloasma generally uses external depigmentation or depigmentation preparations to treat the increase of melanin in the epidermis, but it can only control, not eradicate chloasma

Method used

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  • Traditional Chinese medicine for treating chloasma and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] Embodiment 1 The preparation of capsules of the present invention

[0028] Recipe: 20 parts of wood steamed buns, 23 parts of Ophiopogon japonicus, 28 parts of Xuefeng vine, 30 parts of velvety indigo, 30 parts of rice ball root, 21 parts of angelica, 10 parts of linden, 9 parts of Laojunxu, 13 parts of fungus 12 parts of mulberry, 7 parts of Bauhinia bark, 9 parts of red sugar, 4 parts of fat sea.

[0029] Preparation method: Take the prescription amount of the above-mentioned Chinese medicinal materials and crush them into coarse powder, add an ethanol solution with a volume concentration of 75% according to 8 times the total weight of the coarse powder, reflux and extract three times, the reflux time is 3 hours, filter, recover ethanol from the filtrate, and cool and filter Concentrate into a traditional Chinese medicine extract with a relative density of 1.10-1.20; dry, pulverize into fine powder, and pack into capsule shells to obtain capsules, 0.5g / grain.

Embodiment 2

[0030] Embodiment 2 Preparation of capsules of the present invention

[0031] Recipe: 22 parts of wood steamed buns, 25 parts of Ophiopogon japonicus, 30 parts of Xuefeng vine, 32 parts of velvety indigo, 32 parts of rice ball root, 23 parts of angelica, 12 parts of linden, 11 parts of Laojunxu, 15 parts of fungus 14 parts of mulberry, 9 parts of Bauhinia bark, 11 parts of red sugar, 6 parts of fat sea.

[0032] The preparation method is the same as in Example 1.

Embodiment 3

[0033] Embodiment 3 Preparation of capsules of the present invention

[0034] Recipe: 21 parts of wood steamed buns, 24 parts of Ophiopogon japonicus, 29 parts of Xuefeng vine, 31 parts of velvety indigo, 31 parts of rice ball root, 22 parts of angelica, 11 parts of linden, 10 parts of Laojunxu, and 14 parts of fungus 13 parts of mulberry, 8 parts of Bauhinia bark, 10 parts of red sugar, 5 parts of fat sea.

[0035] The preparation method is the same as in Example 1.

[0036] (2) Acute and chronic toxicity experiments

[0037] Preliminary experiments show that the traditional Chinese medicine of the present invention has very little toxicity and cannot detect LD 50 , therefore, feed according to the maximum consumption.

[0038] 1 Animal acute toxicity test

[0039] Test drugs: the Chinese medicine capsules prepared in Examples 1-3 of the present invention are numbered A, B, and C. Animals used in the test: ordinary NIH mice, weighing 21g±6g, half male and half female, an...

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Abstract

The invention discloses a traditional Chinese medicine for treating chloasma and belongs to the technical field of traditional Chinese medicines. The traditional Chinese medicine is prepared from the following Chinese medicinal materials: climbing fig fruits, dwarf lilyturf tubers, smoothfruit ventilago roots or stems, indigofera stachyodes lindl., scarlet kadsura roots, figs, geum urbanum, sandhill tylophora roots, auricularia, mulberry fruits, Chinese redbud barks, brown granulated sugar and boat-fruited scaphium seeds. The traditional Chinese medicine disclosed by the invention is reasonable in combination of Chinese medicinal materials, has the efficacies of nourishing yin, tonifying the kidneys, promoting the circulation of blood, replenishing blood, dredging collaterals, dissipating stasis, lubricating the intestines and relaxing the bowels, and can be used for treating chloasma radically. The traditional Chinese medicine has the advantages of significant effect and high treatment rate, has no toxic or side effects and is safe.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine, and in particular relates to a traditional Chinese medicine for treating chloasma. Background technique [0002] Melasma, also known as liver spots, is a common acquired hyperpigmentation skin disease that occurs on the face. It occurs in sun-exposed parts and aggravates after sun exposure. Young and middle-aged women are more common. The course of the disease is chronic and there are no obvious symptoms. The state of an illness has certain seasonality, summer is heavy and winter is light. The average optical density value of the pigment along the area is greater than 20% of the average optical density value of the face itself. Occur in women, especially during pregnancy, postpartum and women taking oral contraceptives. The rash is symmetrically distributed on the face, forehead, cheeks, both sides of the back of the nose, around the lips, and the skin of the chin. Blurr...

Claims

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Application Information

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IPC IPC(8): A61K36/8968A61P17/00
Inventor 崔合芳
Owner 崔合芳
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