Drug for intrapleural hyperthermic perfusion therapy

Abstract

The invention discloses a drug for intrapleural hyperthermic perfusion therapy, and is used for solving the therapy problem of cancerous hydrothorax. The drug is characterized by being prepared from the medicinal raw materials including rhizoma arisaematis, folium eucalypti, denseflower bulbophyllum herb, mussel, fragrant sarcococca herb, periostracum cicada, motherwort fruit, sweet clover, kaempferiae, fruits of polygonum orientale and sargassum fusiforme. Clinical experiments prove that the drug disclosed by the invention has good curative effect and higher safety for treating cancerous hydrothorax; and therefore, the drug is worthy of being clinically applied and popularized.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine, in particular to a medicine for pleural hyperthermic perfusion therapy. Background technique [0002] Hyperthermic perfusion therapy is a new therapy for tumors treated by hyperthermia. Its principle is to use physical energy to heat the liquid and infuse it into the tumor site, so that the temperature of the tumor tissue rises to the effective treatment temperature and maintains it for a certain period of time. The difference in temperature tolerance can achieve the therapeutic purpose of making tumor cells apoptosis without damaging normal tissues. [0003] For tumor patients who have already developed cancerous pleural effusion, the pleural cavity is filled with fluid. It is a new idea and theory in recent years to perform hyperthermic pleural perfusion therapy while draining pleural effusion. At present, there are two main perfusion fluids for hyperthermic pleural perfusion therap...

AI Technical Summary

Problems solved by technology

At present, there are two main perfusion fluids for hyperthermic pleural perfusion therapy: one is normal saline, which has poor timeliness in controlling pleural effusion and has a high recurrence rate; the other is chemotherapy drugs, such as cisplatin and nedaplatin, whose mechanism of action lies in the local Anti-cancer and promotion of pleural adhesions, but clinically, due to excessive adhesion promotion, a large amount of cellulose is deposited on the pleura, capillaries and fibroblasts in the pleura grow into the cellulose, become granulation tissue, and become thicker The dense, dense capsule forms an organized pleural fibrous plate, which wraps the lung tissue extensively and hard, lacks elasticity, restricts thoracic activity, severely reduces respiratory function, and increases the recurrence of pleural effusion.

[0004] Therefore, there is still a lack of clinically effective pleural perfusion fluid that can effectively improve respiratory function and reduce the recurrence rate.