A kind of silymarin extraction method using edible grade ethanol as extraction solvent
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A technology for food-grade ethanol and extraction solvent, which is applied in the field of silymarin extraction and can solve problems such as blank preparation methods
Active Publication Date: 2019-03-15
辽宁沃德药业有限公司
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Abstract
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Problems solved by technology
[0007] Looking at these extraction process analyzes all have a common shortcoming, that is, these extraction solvents are all chemical products. For users who use health food as the purpose, the products extracted by these processes are subject to certain restrictions in the food industry. Foreign users prefer A silymarin product that can use edible ethanol as an extractant. According to the research of the applicant, the preparation method of this production process is still blank
Method used
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Examples
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Embodiment 1
[0022] Example 1, Laboratory Extraction (Small Experiment).
[0023] (1) Use a screw oil press to extract most of the oil from the air-dried and air-dried milk thistle seeds, and put 500 grams of cake powder into a Soxhlet extractor.
[0024] (2) It is connected to the whole set of Soxhlet extractor and adopts the electric heating mantle heating system.
[0025] (3) Inject 1500-2000ml of food-grade ethanol from the top of the cooling tube of the Soxhlet extractor, and inject the ethanol through the cake powder (material layer) into the round bottom flask at the bottom (pumice is added in the flask to prevent bumping).
[0026] (4) Turn the control knob of the electric heating mantle, adjust the heating electric power, and increase the temperature slowly until the ethanol in the flask boils. At this time, ethanol vapor rises to the top cooler and begins to trickle into the material layer, and the time is started.
[0027] (5) Extract for 16 hours. After the last reflux is comp...
Embodiment
[0029] Embodiment 2, workshop-level production example.
[0030] (1) The oil extraction treatment of milk thistle seeds is as in Example 1.
[0031] (2) Take 1000kg of milk thistle cake powder and put it into a 1.3 cubic meter multifunctional extraction tank.
[0032] (3) Inject an appropriate amount of food-grade ethanol 1800kg from the liquid injection pipe on the top of the extraction tank, and the liquid level is higher than the upper edge of the material layer.
[0033] (4) Static immersion for 4 hours, open the liquid discharge valves on the top and bottom of the extraction tank, put the extract liquid impregnated with cake powder into the evaporation tank at a certain flow rate, and at the same time, fresh solvent is injected from the liquid injection pipe on the top of the extraction tank to connect with the tank The bottom discharge liquid is injected into the material layer in the tank at the same flow rate, so that the solvent entering and flowing out reaches a dyn...
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Abstract
The invention provides a method for extracting silymarin by using food-grade ethanol as an extracting solvent. The method is characterized by comprising the following steps: (1) removing fatty oil from silybum marianum seeds; (2) grinding oil-pressed cake, and putting into an extraction tank; (3) injecting a proper amount of food-grade ethanol from the top end of the extraction tank; (4) putting an extracting solution which is immersed with cake powder into an evaporation tank after static immersion, and injecting a fresh solvent into the charge layer in the extraction tank from the top end of the extraction tank to dynamically balance solvents flowing in and out of the extraction tank; (5) dynamically extracting; (6) concentrating; (7) stopping concentrating until the density is 1.2g / ml, and transferring fluid extract obtained by concentration into an extract washing machine; (8) degreasing for the second time; (9) baking; (10) grinding, and screening products with different specifications for users. According to the method, food-grade ethanol is used as an extracting agent instead of chemical raw materials in the prior art, so that obstacles in the march of silymarin forward to the field of health foods are cleared.
Description
technical field [0001] The invention relates to a method for extracting silymarin, in particular to a method for extracting silymarin using food-grade ethanol as an extraction solvent, which belongs to the extraction and purification technology for extracting active ingredients from silymarin seeds. Background technique [0002] Milk thistle is also known as milk thistle, mouse thistle, artichoke, milk pheasant, etc., and its Latin name is Silybum mariaum. It is native to the Mediterranean coast and is wildly distributed in the grasslands of western Asia. It is a biennial or annual herb. It is currently in Europe. It is cultivated in Asia, Africa and North and South America. [0003] Milk thistle is a kind of medicinal economic crop. In the 1960s and 1970s, a group of scientists such as German botanist H. Wagner and Japanese botanist Tsunematsu found that the seeds contained silymarin, a drug for treating diseases. , invented the extraction technology of this drug and deter...
Claims
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Application Information
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