Methods and uses of an extract from olive leaf in management of type 2 diabetes
A type 2 diabetes, extract technology, applied in the field of olive leaf extract in the treatment of type 2 diabetes, can solve the problems of no decision-making, lack of knowledge of human subjects' health effects, no signature, etc.
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Embodiment 1
[0066] method:
[0067] Study Population and Recruitment
[0068] Men aged 35-55 years were recruited into the trial in February 2010 through newspaper advertisements. Participants are required to have a BMI of 25-30kg / m 2 between. Exclusion criteria were smokers, users of medications that might affect insulin sensitivity, or patients with diabetes. People taking antihypertensive or lipid-lowering drugs were enrolled, but they were required to be on a stable dose for at least 6 months before starting the study and were discouraged from changing doses throughout the study.
[0069] Research design
[0070] The design is a randomized, double-blind, placebo-controlled crossover trial. Participants were randomized to receive either olive leaf extract or a placebo for 12 weeks. Participants are randomly assigned to experimental groups using a computer-generated random number. After a 6-week washout phase, participants crossed over to the opposite intervention. Participants ...
Embodiment 2
[0094] In this example, patients who were clinically diagnosed with type 2 diabetes and whose condition was controlled with medication were started on olive leaf extract. The extract is taken as a single dose of 4 capsules per day with a glass of water. Capsules are a commercial product from Comvita Ltd. The polyphenol dosage in 4 OLE capsules is approximately 50mg oleuropein and 10mg hydroxytyrosol.
[0095] Results before and after starting treatment include:
[0096] 1. Within 47 days of taking the extract, the HbA1c score changed from 52Mmols to 45Mmols;
[0097] 2. Lose weight by 7kg within 47 days;
[0098] 3. After 47 days of treatment, patients' uncontrolled assessment of their own general health ranging from "lazy and tired" to "feeling very good at the moment" and "more energy throughout the day";
[0099] 4. After 47 days of treatment, cholesterol decreased;
[0100] 5. Stop taking metformin, a prescription drug used to treat diabetes;
[0101] 6. After 47 day...
Embodiment 3
[0104] In this example, other type 2 diabetic patients also started taking olive leaf extract as a single dose of 4 capsules per day with a glass of water. Capsules are a commercial product from Comvita Ltd. The polyphenol dosage in 4 OLE capsules is approximately 50mg oleuropein and 10mg hydroxytyrosol.
[0105] Results before and after starting treatment include:
[0106] 1. After taking the extract for 9 months, the HbA1c score changed from 9.7 (77Mmols) to 7.2 (63Mmols);
[0107] 2. Lose weight by 8.5kg within 9 months;
[0108] 3. Since starting to take olive leaf extract, patients' uncontrolled evaluation of their energy levels has "greatly increased";
[0109] 4. Eliminates the need for immediate insulin injections prior to starting the trial.
[0110] As in Example 2, the above results clearly demonstrate that olive leaf extract at least alleviates the symptoms of type 2 diabetes, such as lowering the patient's blood sugar level (as measured by the HbA1c score), in...
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