A frog heart perfusion experimental device

Abstract

The invention relates to an experimental device for medical function and physiology, in particular to an improved experimental device for frog heart perfusion. The improved experimental device comprises a buffer tube, a three-way buffer artery tube, an artery plug, an artery cannula, a quantitative drop device, a venous cannula and a venous plug, wherein an opening is formed in the top of the buffer tube; the three-way buffer artery tube is connected with the buffer tube; the artery plug is connected with one branch tube of the three-way buffer artery tube; the artery cannula is connected with the other branch tube of the three-way buffer artery tube; the quantitative drop device is connected with the artery cannula; the venous cannula is arranged below the quantitative drop device; the venous plug is connected with the venous cannula; the artery plug is inserted into an aorta of a frog heart; the venous plug is inserted into a postcaval vein of the frog heart. According to the improved experimental device for the frog heart perfusion, disclosed by the invention, the buffer action for perfused liquid ejected in the blood ejection process of the frog heart is realized, uninterrupted dropwise outflow of the perfused liquid can be kept, the perfused liquid can flow at the systole and diastole of the heart, and quantitative record of liquid can be realized by the quantitative drop device.

Description

technical field [0001] The invention relates to a medical functional science and physiology experimental device, in particular to a frog heart perfusion experimental device. Background technique [0002] Isolated heart perfusion is one of the important means of studying heart function, and it is widely used in teaching and scientific research in medicine, biology, and pharmacy. Using the isolated heart perfusion system can visually observe the activity of the heart, and study the effects of cardiac diastolic and systolic function, heart rate and rhythm changes, preload and postload, and various body fluid factors on cardiac function. The isolated heart perfusion using the frog heart is a more commonly used model, and it has been widely used because of its stability and economy. To conduct isolated heart perfusion experiments, first of all, it is necessary to ensure that the heart survives in vitro for a long time, and then perform perfusion and apply experimental factors ac...

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Problems solved by technology

[0004] One of the purposes of the present invention is to provide a frog heart perfusion experimental device to provide a buffer for the perfusate injected during the frog heart ejection process in order to solve the problem that the injection of perfusate during diastole cannot be guaranteed and it is inconvenient to quantify the liquid injected by the frog heart Function, it can keep the perfusate dripping out continuously, and the perfusate flows out during systole and diastole, and the liquid quantitative recording can be realized through the drip recording device

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