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Traditional Chinese medicine combination for migraine treatment and production method thereof

A composition and technology for migraine, applied in the field of traditional Chinese medicine, can solve the problems of large toxic and side effects of western medicine, unsatisfactory treatment effect of traditional Chinese medicine, unsustainable treatment effect and the like

Inactive Publication Date: 2015-09-16
QINGDAO HUAREN TECH INCUBATOR
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] The purpose of the present invention is to overcome the existing western medicines for migraine with large toxic and side effects, difficult to sustain the therapeutic effect, and unsatisfactory Chinese medicine treatment effect. It has the advantages of strong pertinence, good curative effect, short cycle, low price, no toxic and side effects, etc., and can make patients willing to accept it, and can better care and treat pure Chinese medicine preparations for migraine

Method used

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  • Traditional Chinese medicine combination for migraine treatment and production method thereof

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preparation example Construction

[0041] The present invention also provides a preparation method of the above-mentioned traditional Chinese medicine composition, comprising:

[0042] Mix the components in the raw material components in proportion, soak in 5-8 times the amount of water for 12-24 hours, extract the volatile oil with steam distillation, save the distilled medicinal residue and medicinal liquid separately, and recover the medicinal liquid under reduced pressure Concentrate to a relative density of 1.05-1.15 at 70-90°C to obtain A; the above-mentioned volatile oil is dissolved in ethanol at a ratio of 1:1, and the colloid milling method is used, and the ratio of volatile oil to β-cyclodextrin is 1:6-10, β -The ratio of cyclodextrin to water is 1:1-3, adopt appropriate grinding speed to grind for 15-30 minutes for clathrate, obtain paste, dry at 40-60°C, and pulverize to obtain clathrate B; Continue to extract the residue with 60-80% ethanol under reflux for 1-3 times, each time 6-10 times the solv...

Embodiment 1

[0047] Get 8 parts by weight of benzoin, 6 parts by weight of agrimony, 4 parts by weight of nutmeg, 5 parts by weight of Alisma, 4 parts by weight of agarwood, 8 parts by weight of safflower, 8 parts by weight of jujube, 5 parts by weight of Ligustrum lucidum, and Asarum 4 parts by weight, 7 parts by weight of Prunella vulgaris, 10 parts by weight of cassia seed, 8 parts by weight of lovage, 12 parts by weight of Puhuang, 5 parts by weight of Fangfeng, 6 parts by weight of chrysanthemum, mixed in proportion; soaked in 5 times the amount of water for 12 hours, water The steam distillation method extracts the volatile oil, and the distilled medicinal residue and medicinal liquid are stored separately, and the medicinal liquid is recovered under reduced pressure and concentrated to a relative density of 1.05 at 70°C to obtain A; the above-mentioned volatile oil is dissolved by adding ethanol at a ratio of 1:1, and the colloidal milling method is used. The ratio of volatile oil to...

Embodiment 2

[0051] Take 12 parts by weight of benzoin, 10 parts by weight of agrimony, 10 parts by weight of nutmeg, 10 parts by weight of Alisma, 9 parts by weight of agarwood, 16 parts by weight of safflower, 17 parts by weight of jujube, 11 parts by weight of Ligustrum lucidum, and Asarum 10 parts by weight, 14 parts by weight of Prunella vulgaris, 18 parts by weight of Semen Cassiae, 12 parts by weight of lovage, 18 parts by weight of Puhuang, 10 parts by weight of Fangfeng, 12 parts by weight of Chrysanthemum, mixed in proportion; Mix them according to the proportion, soak in 8 times the amount of water for 24 hours, extract the volatile oil by steam distillation, save the distilled medicinal residue and medicinal liquid, recover and concentrate the medicinal liquid under reduced pressure until the relative density is 1.15 at 90°C to obtain A; the above-mentioned volatile oil Add ethanol at a ratio of 1:1 to dissolve, use the colloid milling method, the ratio of volatile oil to β-cycl...

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Abstract

The invention provides a traditional Chinese medicine combination for migraine treatment. The traditional Chinese medicine combination comprises raw material composition of benzoin, herba agrimoniae, nutmeg, alisma, agilawood, safflower, fructus choerospondiatis, glossy privet fruit, asarum, selfheal, cassia seed, radix angelicae pubescentis, cattail pollen, Chinese parsnip and chrysanthemum. Compared with the pure western medicine treatment, the index of the migraine can be well reduced, the clinical manifestations of patients are improved, the further worsening of the migraine is prevented, and meanwhile the toxic side effects are not produced and the safety and the degree of comfort are high.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine, in particular to a traditional Chinese medicine composition for treating migraine and a preparation method thereof. Background technique [0002] Migraine is one of the common types of headaches in clinical practice. Its lesion is characterized by recurrent headaches. It is commonly known as "migraine wind" in traditional Chinese medicine and vascular headache in Western medicine. The main clinical manifestation of patients is pain on one or both sides of the head. Throbbing or persistent pain with frequent attacks. It is mainly caused by intracranial arterial constriction or expansion, and is more common in women. The epidemiological survey of the incidence rate of men and women is 6% for men and 18% for women, and the most frequent age group is 25-35 years old. [0003] Among migraines, migraine without aura (generalized migraine) is the most common: episodic moderate to s...

Claims

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Application Information

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IPC IPC(8): A61K36/884A61P25/06
Inventor 孙霞
Owner QINGDAO HUAREN TECH INCUBATOR
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