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Soluble florfenicol powder and preparation method thereof

A florfenicol and soluble technology, which is applied in the field of soluble florfenicol powder and its preparation, can solve the problems of bad odor of florfenicol, complicated preparation process, application limitation and the like, and achieves reduction of treatment cost and simple method and process. , the effect of low equipment cost

Active Publication Date: 2015-09-23
GUANGDONG GALLOPER VETERINARY PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0009] In order to solve the technical problems in the prior art that the application of florfenicol is limited due to its bad smell and irritation, poor water solubility and complicated preparation process, an object of the present invention is to provide a kind of soluble florfenicol powder

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0035] A kind of soluble florfenicol powder, it is made up of following components by weight percentage: florfenicol 10%, polyvinylpyrrolidone K30 5%, macrogol 4000 10%, porcine mastic 5%, glucose 70% % (the content of each component is based on the weight of 100kg of soluble florfenicol powder).

[0036] The method for preparing above-mentioned soluble florfenicol powder comprises the following steps:

[0037] 1) Weigh each component according to the above weight percentage, take florfenicol, polyvinylpyrrolidone K30, polyethylene glycol 4000 and porcine frankincense according to the weight percentage in the formula, and crush them through an 80-mesh sieve;

[0038] 2) Put the materials in step 1) into the three-dimensional mixer in sequence for the first mixing, and the mixing time is 30 minutes to obtain the first mixture;

[0039] 3) After crushing the glucose through an 80-mesh sieve, add it to a three-dimensional mixer for the second mixing with the first mixture, and t...

Embodiment 2

[0042] A kind of soluble florfenicol powder, it is made up of the following components by weight percentage: florfenicol 8%, polyvinylpyrrolidone K30 10%, milk essence 5%, soluble starch 77% (each component content according to The weight of soluble florfenicol powder is 100kg).

[0043] The method for preparing above-mentioned soluble florfenicol powder comprises the following steps:

[0044] 1) Weigh each component according to the above weight percentage, take florfenicol, polyvinylpyrrolidone K30, and milk essence according to the weight percentage in the formula, and crush them through a 60-mesh sieve;

[0045] 2) Add the materials in step 1) into the two-dimensional mixer in turn for the first mixing, and the mixing time is 10 minutes to obtain the first mixture;

[0046] 3) After passing the soluble starch through a 60-mesh sieve, add it to the three-dimensional mixer and mix it with the first mixture for the second time. The mixing time is 30 minutes to obtain the sec...

Embodiment 3

[0049] A kind of soluble florfenicol powder, it is made up of following components by weight percentage: florfenicol 5%, polyvinyl alcohol 1%, polyvinylpyrrolidone K30 9%, lemon essence 2%, lactose 83% ( The content of each component is based on the weight of 100kg of soluble florfenicol powder).

[0050] The method for preparing above-mentioned soluble florfenicol powder comprises the following steps:

[0051] 1) Weigh each component according to the above weight percentage, take florfenicol, polyvinyl alcohol, polyvinyl pyrrolidone K30, and lemon flavor according to the weight percentage in the formula, and crush them through a 100-mesh sieve;

[0052] 2) Add the materials in step 1) into the three-dimensional mixer in turn for the first mixing, and the mixing time is 20 minutes to obtain the first mixture;

[0053] 3) After pulverizing the lactose through a 100-mesh sieve, add a two-dimensional mixer and mix it with the first mixture for the second time. The mixing time is...

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PUM

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Abstract

The invention belongs to the fields of animal medicine and manufacturing thereof, and in particular relates to soluble florfenicol powder and a preparation method thereof. The invention provides soluble florfenicol powder which is prepared from the following components in percentage by weight: 1 to 10% of florfenicol, 1 to 15% of cosolvent, 1 to 5% of phagostimulant and the balance of filler. The soluble florfenicol powder disclosed by the invention is better in solubility in water and can realize drug therapy in a drinking water manner when sick animals do not eat feed; original unpleasant odor and irritation of florfenicol are covered; feed intake of medicine by the sick animals can be ensured effectively; a good treatment effect within a short period is realized, and treatment cost is reduced, so that the soluble florfenicol powder is popular among a majority of farmers.

Description

technical field [0001] The invention belongs to the field of animal medicine and its manufacture, and in particular relates to a soluble florfenicol powder and a preparation method thereof. Background technique [0002] Florfenicol, as a third-generation floromycin broad-spectrum antibacterial drug for veterinary medicine, is mainly used for the prevention and treatment of bacterial diseases such as livestock, poultry and fish caused by sensitive bacteria. [0003] The poor water solubility of the florfenicol raw material itself affects the development of its soluble powder to a certain extent, thereby reducing the absorption and bioavailability of the drug in animals. In addition, florfenicol powder has a single administration route, which is not conducive to its popularization and application in aquaculture production. [0004] Chinese Invention Patent Application No. CN102697730A discloses a soluble florfenicol powder and a preparation method thereof. The product it prov...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/14A61K31/165A61K47/32A61K47/34A61K47/26A61P31/04
Inventor 李云黄剑华
Owner GUANGDONG GALLOPER VETERINARY PHARMA
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