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Application of natural fatty acid disinfectant to preparation of porcine reproductive and respiratory syndrome virus preparations

A technology for respiratory syndrome and fatty acid, applied in the directions of disinfectants, respiratory diseases, applications, etc., can solve problems such as poor immune effect

Inactive Publication Date: 2015-09-30
季建萍
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0018] 2. Stillbirth accounts for 20% of litter size;
[0019] 3. The mortality rate of piglets exceeds 25% within 1 week after birth
The inactivated vaccine is safe, but the immune effect is slightly worse. The basic immunization is performed twice, with an interval of 3 weeks, and 4 ml per head is injected intramuscularly each time. After that, immunization is performed once every 5 months, with 4 ml per head.

Method used

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  • Application of natural fatty acid disinfectant to preparation of porcine reproductive and respiratory syndrome virus preparations

Examples

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preparation example Construction

[0046] 1.3 Preparation and dilution of virus: porcine reproductive and respiratory syndrome virus JXA1, diluted to 10 with sterilized deionized water before inoculation 5 TCID 50 / ml virus suspension, spare.

[0047] 1.4 Cells and culture medium

[0048] Cells: Marc-145 cell line

[0049] Culture medium: DMEM cell culture medium with 8% fetal bovine serum, DMEM cell culture medium with 2% fetal bovine serum.

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Abstract

The invention discloses application of a natural fatty acid disinfectant to preparation of porcine reproductive and respiratory syndrome virus preparations. The content of total fatty acid in the natural fatty acid disinfectant is 9.9wt%-11.9wt%. The natural fatty acid disinfectant is prepared from pelargonic acid, caprylic acid, capric acid and a solvent, wherein the content of pelargonic acid is 4.6wt%-5.5wt%, the content of caprylic acid is 3.1wt%-3.7wt%, and the content of capric acid is 2.1wt%-2.7wt%. The porcine reproductive and respiratory syndrome virus killing rate of the natural fatty acid disinfectant is 100%.

Description

technical field [0001] The invention relates to the technical field of disinfectant application, in particular to the application of a natural fatty acid disinfectant in the preparation of preparations for killing porcine reproductive and respiratory syndrome virus. Background technique [0002] Porcine reproductive and respiratory syndrome (Porcine reproductive and respiratory syndrome, PRRS) has been popular since the late 1980s. It was officially named by the International Veterinary Bureau in 1992. It mainly affects pigs, especially sows, and the disease seriously affects their reproductive function. The main clinical features are miscarriage, stillbirth, mummified fetus, weak fetus, dyspnea, and transient skin cyanosis in both ears during the course of the disease, so it is also called PRRS. [0003] In the late 1980s and early 1990s, the disease spread rapidly to all pig-raising countries in the world, and it was more likely to be prevalent in areas with dense pig herd...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/20A61P31/14A61P11/00A01N37/02A01P1/00
Inventor 季建萍
Owner 季建萍
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