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Oral care products with anti-helicobacter pylori efficacy containing hawthorn kernel alcohol extract

An anti-Helicobacter pylori and oral care technology, applied in the field of daily chemicals, can solve the problems of reduced therapeutic effect, recurrent disease, loss, etc., and achieve the effect of killing Helicobacter pylori, stable dosage components, and simple extraction methods

Active Publication Date: 2018-10-26
杭州华胄生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The disadvantages of the prior art are: 1. Kill a large number of beneficial bacteria, which easily leads to repeated outbreaks of the disease. 2. The taking of large doses of multiple antibiotics increases the drug resistance of Helicobacter pylori, and the drug resistance of the bacteria makes the original effective antibiotics less effective. The treatment effect is reduced or lost, which increases the difficulty of treatment and medical costs for patients
Although there are some Chinese herbal health care toothpastes on the market, the antibacterial effect is not ideal enough, especially it does not have the effect of killing Helicobacter pylori

Method used

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  • Oral care products with anti-helicobacter pylori efficacy containing hawthorn kernel alcohol extract
  • Oral care products with anti-helicobacter pylori efficacy containing hawthorn kernel alcohol extract
  • Oral care products with anti-helicobacter pylori efficacy containing hawthorn kernel alcohol extract

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] Toothpaste with anti-Helicobacter pylori effect extracted from hawthorn rib alcohol, composed of the following components by weight: 90 parts of dibasic calcium phosphate, 25 parts of water, 7 parts of sorbitol, 3 parts of hydrated silica, polyethylene glycol -8 3 parts, 4 parts of propylene glycol, 2 parts of sodium lauryl sulfate, 3 parts of cellulose gum, 3 parts of hydroxyethyl cellulose, 3 parts of flavor, 3 parts of sodium benzoate, 3 parts of saccharin sodium, alcohol extract of hawthorn core 3 copies.

[0027] Among them, the alcohol extract of hawthorn nucleus is prepared by the following method:

[0028] 1) Take the clean dried hawthorn nucleus and crush it to obtain hawthorn nucleus powder;

[0029] 2) According to the ratio of material to liquid (g / ml) 1:10, in step 1) 100g of hawthorn nucleus powder was prepared by adding 70% ethanol 1000mL, and refluxing for 4h at 80°C to obtain the extract;

[0030] 3) Filter the extract under reduced pressure on filter paper to...

Embodiment 2

[0035] A mouthwash containing an alcohol extract of hawthorn nucleus with anti-Helicobacter pylori effect, consists of the following components by weight: 95 parts of water, 15 parts of sorbitol, 7 parts of propylene glycol, 8 parts of xylitol, PEG-400 poly 8 parts of ethylene glycol, 3 parts of dimethyl glycyrrhizinate, 3 parts of sodium benzoate, 2 parts of flavor, 3 parts of hawthorn nucleus alcohol extract.

[0036] The preparation method of the ethanol extract of hawthorn nucleus is the same as in Example 1.

Embodiment 3

[0038] A chewing gum with anti-Helicobacter pylori effect containing an alcohol extract of hawthorn nucleus, consisting of the following parts by weight: 35 parts of xylitol, 25 parts of gum base, 17 parts of sorbitol, 17 parts of maltitol liquid, D- 8 parts of mannitol, 170 parts of citric acid, 110 parts of phospholipids, 35 parts of aspartame, 35 parts of flavor, 3 parts of hawthorn core alcohol extract.

[0039] The preparation method of the ethanol extract of hawthorn nucleus is the same as in Example 1.

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Abstract

The invention discloses an oral care product containing hawthorn seed alcohol extracts and having a helicobacter pylori resistant function. The oral care product is characterized by comprising the hawthorn seed alcohol extracts. The traditional Chinese medicine oral care product is provided, a medicine extraction method is simple, dosage and ingredient are stable, and the product can directly go deep into an oral cavity. The product can not cause disturbance to the environment in the oral cavity after long-term use and is free of side effects. The effects of killing helicobacter pylori and effectively preventing helicobacter pylori from oral transmission are achieved besides the aims, similar to those of oral care products such as Chinese herbal medicine health care toothpaste, of eliminating ozostomia, treating dental ulcer and resisting common oral pathogens to diminish inflammation.

Description

Technical field [0001] The invention belongs to the technical field of daily chemicals, and specifically relates to an oral care product containing an alcohol extract of hawthorn nucleus and having the effect of anti- Helicobacter pylori. Background technique [0002] Helicobacter pylori, English name Helicobacter pylori, referred to as Hp. Helicobacter pylori is a highly infectious pathogen with a high infection rate. In 1983, Australian scholars Barry J. Marshall and Robin Warren J. Robin Warren first isolated and detected Helicobacter pylori in gastric mucosal biopsy tissues of patients with gastritis. In 1989, Australian scholar Krajden detected HP in the dental plaque of the oral teeth of gastritis patients, and confirmed that it was the same as Hp in the stomach from the molecular level. Hp is an oral infectious disease, and oral Hp is an important reservoir of stomach Hp. Helicobacter pylori has a major damage to human health: it is the first type of carcinogen that ind...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K8/9789A61K36/734A61K9/46A61K9/12A61Q11/00A61P1/02A61P31/04A23G4/12A23G3/48
Inventor 严杰林世恩葛玉梅
Owner 杭州华胄生物科技有限公司
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