Cistanche extract phenylethanol total glycosides flexible nano-liposome freeze-dried powder and preparation method thereof
A Cistanche extract and nano-liposome technology are applied in the fields of pharmaceutical formulas, cosmetic preparations, and dressing preparations, etc., which can solve the problem that liposome particles are easily oxidized, active substances leak, and limit the application of liposomes. and other problems, to achieve the effect of prolonging the action time, good encapsulation rate, and improving the effect of transdermal absorption
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Embodiment 1
[0022] Example 1: The flexible nano-liposome freeze-dried powder of phenylethanol total glycosides from Cistanche deserticola extract, raw materials include 1 to 10 parts by weight of total phenylethanol glycosides from Cistanche deserticola extract, 60 to 140 parts of egg Phospholipids, 10 to 90 parts of cholesterol and 10 to 120 parts of surfactants, and the flexible nano-liposome freeze-dried powder of phenylethanol total glycosides extracted from Cistanche are obtained by the following preparation method: the first step, to the required A certain amount of lecithin and cholesterol are added with an organic solvent until the lecithin and cholesterol are completely dissolved in the organic solvent to obtain a solution; in the second step, the solution is evaporated under reduced pressure, and when the solution is evaporated under reduced pressure, a film appears , add the organic mixed solution to the dissolving liquid until the film is dissolved to obtain the oil phase; the ...
Embodiment 2
[0023] Example 2: The flexible nanoliposome freeze-dried powder of phenylethanol total glycosides from Cistanche deserticola extracts, raw materials include 1 or 10 parts by weight of total phenylethanol glycosides from Cistanche deserticola extract, 60 or 140 parts of egg Phospholipids, 10 or 90 parts of cholesterol and 10 or 120 parts of surfactants, Cistanche extract phenylethanol total glycosides flexible nano-liposome freeze-dried powder is obtained by the following preparation method: the first step, to the required A certain amount of lecithin and cholesterol are added with an organic solvent until the lecithin and cholesterol are completely dissolved in the organic solvent to obtain a solution; in the second step, the solution is evaporated under reduced pressure, and when the solution is evaporated under reduced pressure, a film appears , add the organic mixed solution to the dissolving liquid until the film is dissolved to obtain the oil phase; the third step, add the...
Embodiment 3
[0024] Embodiment 3: The flexible nanoliposome freeze-dried powder of phenylethanol total glycosides of Cistanche deserticola extract, raw materials include 6 to 10 parts by weight of total phenylethanol glycosides of Cistanche deserticola extract, 80 to 100 parts of egg Phospholipids, 60 to 90 parts of cholesterol and 80 to 110 parts of surfactants, Cistanche genus extract phenylethanol total glycosides flexible nano-liposome freeze-dried powder are obtained according to the following preparation method: the first step, to the required A certain amount of lecithin and cholesterol are added with an organic solvent until the lecithin and cholesterol are completely dissolved in the organic solvent to obtain a solution; in the second step, the solution is evaporated under reduced pressure, and when the solution is evaporated under reduced pressure, a film appears , add the organic mixed solution to the dissolving liquid until the film is dissolved to obtain the oil phase; the thir...
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