Preparing method for medicine for treating peptic ulcer

A technology for peptic ulcer and medicine, which is applied in the field of preparation of medicine for treating peptic ulcer, can solve the problems of loss, and the active ingredient is not easily soluble in water, and achieves the effect of improving the efficacy and activity of the medicine.

Inactive Publication Date: 2016-01-20
CHENGDU HENGLING TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At the same time, traditional Chinese medicinal materials are mostly decocted in water, but some active ingredients are not easily soluble in water, or are lost during the decoction process. Therefore, in order to make better use of medicinal material resources, it is necessary to prepare pharmaceutical compositions method for research

Method used

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  • Preparing method for medicine for treating peptic ulcer
  • Preparing method for medicine for treating peptic ulcer
  • Preparing method for medicine for treating peptic ulcer

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0032] The preparation of embodiment 1 medicine of the present invention

[0033] Atractylodes macrocephala 10g, Poria cocos 10g, red bean 10g, astragalus 7.5g, capillary 7.5g, dandelion 7.5g, bitter almond 5g, bellflower 5g, patchouli 5g, dried ginger 2.5g, ginseng 2.5g; take other herbal flavors except ginseng , first add 10 times the amount of 70% ethanol solution to reflux for extraction once, extract for 1 hour, filter, and use the filtrate for later use, decoct the filter residue twice with water, add 8 times the amount of water each time, decoct for 30 minutes each time, and combine the ethanol extract After decocting in water, concentrating, adding ginseng powder, granulating, adding an appropriate amount of magnesium stearate, and compressing into tablets, the pharmaceutical tablet of the present invention is obtained.

Embodiment 2

[0034] The preparation of embodiment 2 medicines of the present invention

[0035] 180g Atractylodes macrocephala, 220g Poria cocos, 220g red bean, 170g astragalus, 170g capillary, 170g dandelion, 120g bitter almond, 120g platycodon, 120g patchouli, 60g dried ginger, 60g ginseng; take other herbs except ginseng, add 10 times Measure 95% ethanol solution for reflux extraction once, extract for 2 hours, filter, filtrate for later use, decoct the filter residue with water twice, add 10 times the amount of water each time, decoct for 20 minutes each time, combine the ethanol extract and water decoction , concentrate, then add ginseng powder, and obtain granules after granulation.

Embodiment 3

[0036] Embodiment 3 preparation of medicine of the present invention

[0037] 220g Atractylodes macrocephala, 180g poria cocos, 180g red bean, 130g astragalus, 130g capillary, 130g dandelion, 80g bitter almond, 80g platycodon, 80g patchouli, 40g dried ginger, 40g ginseng. Take 55% ethanol solution for reflux extraction once, extract for 1 hour, filter, and use the filtrate for later use, decoct the filter residue twice with water, add 8 times the amount of water each time, and decoct for 30 minutes each time, after combining the ethanol extract and water decoction , concentrate, then add ginseng powder, after granulation, then add appropriate amount of magnesium stearate, and compress into tablets to obtain the pharmaceutical tablet of the present invention.

[0038] The beneficial effects of the present invention are further demonstrated through specific test examples below.

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PUM

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Abstract

The invention discloses a preparing method for medicine for treating a peptic ulcer. The preparing method comprises the following operation steps that firstly, raw medicine materials including, by weight, 17-23 parts of ginseng, 7-12 parts of poria cocos, 5-9 parts of oriental wormwood, 5-9 parts of pogostemon cablin, 5-9 parts of raw malt, 3-7 parts of mangnolia officinalis, 3-7 parts of perilla leaves and 3-7 parts of caulis perllae are weighed; secondly, ginseng is taken and ground into power for use, the other medicine materials except ginseng are taken, added with 55-95% v/v ethanol for extraction and then filtered, alcohol extract is obtained for use, filter residues are added with water again to be decocted, the alcohol extract and the water decoction are combined and then concentrated, ginseng powder and auxiliary materials acceptable medically are then added, and the medicine is obtained. The medicine is prepared from few medicine materials through specific dosage proportions, can effectively treat a gastric ulcer, a duodenal ulcer and stomach mucosa erosion, and provides a new pharmacy choice for clinically treating the peptic ulcer. Meanwhile, through pharmacodynamic tests, the modes of alcohol and water dual extraction and ginseng used as powder in the medicine are adopted, pharmacodynamic activity can be improved, and medicine material resources can be easily used economically.

Description

technical field [0001] The invention relates to a preparation method of a medicine for treating peptic ulcer. Background technique [0002] Peptic ulcer mainly refers to chronic ulcers that occur in the stomach and duodenum. Among them, gastric and duodenal ulcers refer to localized circular or oval full-thickness defects of the gastric and duodenal mucosa, the muscularis mucosa is penetrated, and fibrous scars are inevitably left after healing. Covered by epithelium, the muscularis mucosa cannot regenerate. The etiology can be summed up as the self-digestion of gastric mucosa by gastric acid and pepsin or the destruction of gastric mucosal barrier due to various reasons. In recent years, it has been considered that the formation of ulcers has an important relationship with Helicobacter pylori infection in the stomach. [0003] Chronic erosive gastritis, also known as verrucous gastritis or pimple-like gastritis, generally only sees dyspepsia symptoms such as fullness aft...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9068A61P1/04
Inventor 李智叶英谭丰
Owner CHENGDU HENGLING TECH CO LTD
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