Method for preparing children aerosol inhalation medicine

Abstract

The invention discloses a method for preparing children aerosol inhalation medicine to treat children noninfectious coughing. The method is characterized by comprising the steps of 1, conducting volatile oil extraction on pterospermum hetero-phyllum hance, euphorbia maculata, fruits of ailanthus altissima swingle, pseudodrynaria coronans, semen aesculi, cinnamomum camphora, solanum lyratum thumb, flax seeds, artemisia argyi and beautiful sweetgum resin coarse powder, and obtaining mixed volatile oil and decoction dregs for use; 2, evenly mixing wintergreen, fresh gorgon euryale seeds and the decoction dregs obtained in the step 1, conducting water extraction and alcohol precipitation, filtration and alcohol removal, then conducting ultrafiltration with a microporous film, and conducting concentration and drying on filtrate, so that a primary material is obtained; 3, spraying the volatile oil obtained in the step 1 into the primary material obtained in the step 2, conducting even mixing, conducting smashing and screening with a 100-mesh screen, and then conducting sterilization. Clinical experiments prove that the medicine has the advantages of being good in curative effect, high in safety performance and worth clinical application and popularization.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicines, in particular to a preparation method of nebulized inhalation medicine for children. Background technique [0002] Both "Guidelines for the Diagnosis and Treatment of Chronic Cough in Children (Revised in 2013)" and "2013 MIMS Guidelines for Respiratory Diseases" clearly state that cough is divided into infectious cough and non-infectious cough according to the etiology (or pathogen), the so-called non-infectious cough He had cough and pharyngeal discomfort, but no respiratory tract infection. Blood routine examination showed that the white blood cells were not high. The cough was mostly persistent, irritating, and paroxysmal. There was no substantial change in the lung texture. This kind of non-infectious cough is mostly caused by non-infectious factors irritating the respiratory tract, and antibiotic treatment generally does not work. Due to changes in the living environment, the p...

AI Technical Summary

Problems solved by technology

[0004] Therefore, at present, the treatment of non-infectious cough in children mainly relies on traditional Chinese medicine. However, in fact, some children with non-infectious cough are not simply "dry cough". Dry throat, itchy throat, cold air, talking, etc. can cause cough, and some pathology shows that throat Caused by mucus retention under the mucous membranes, because blindly "clearing fire and moistening dryness" cannot obtain good results

The use of antitussive drugs can sometimes reduce the cough reflex through the central antitussive effect in a short period of time, and achieve the purpose of antitussive, but children often have recurrent attacks within one to two weeks, because the mucosal lesions of the posterior pharyngeal wall have not improved , after the effect of antitussive drugs disappears, the cough reflex returns and the symptoms come back

At present, nebulized inhalation is also used for clinical treatment, but the current nebulized inhaled drugs are mainly targeted at the lower respiratory tract. For the mucous membrane of the throat, the local drug effect is not good due to the poor adhesion of the nebulized inhaled drug, but the use of mucous membrane adhesion Excipients may enhance throat mucous membrane irritation and enhance cough