Preparation and application of Al<3+> fluorescent probe based on rhodamine B derivative

A technology of fluorescent probes and derivatives, applied in the direction of fluorescence/phosphorescence, luminescent materials, chemical instruments and methods, etc., to achieve high yield, low detection limit, and good selectivity
CN105348293AInactive Publication Date: 2016-02-24HAINAN MEDICAL COLLEGE
5 Cites 8 Cited by

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
HAINAN MEDICAL COLLEGE
Publication Date
2016-02-24
Estimated Expiration
Not applicable · inactive patent

Smart Images

  • Figure 1
    Figure 1
  • Figure 2
    Figure 2
  • Figure 3
    Figure 3
Patent Text Reader

Abstract

The present invention relates to a fluorescent molecular probe and particularly to preparation and application of a rhodamine B derivative. A preparation method comprises the following steps of enabling a rhodamine B hydrazinolysis product to react with glyoxal in anhydrous ethanol at the room temperature for 6-8 hours, and precipitating a solid to obtain an intermediate compound; and enabling the intermediate to react with ortho-aminophenol in the anhydrous ethanol at the temperature of 70-80 DEG C for 4-6 hours, cooling down the reaction product, then carrying out suction filtration on the precipitated solid, and performing washing, drying and separating to obtain a yellow solid P as shown in a formula 1. The rhodamine B derivative P can be used as a fluorescent probe to implement identification and detection on aluminum ions. According to the present invention, the rhodamine B derivative P obtained by an effective combination means shows good selectivity for Al<3+>, and on the basis of optimizing an experimental condition, detection on the aluminum ions can be implemented. The formula 1 is shown as the specification.
Need to check novelty before this filing date? Find Prior Art

Description

technical field

[0001] The invention relates to a fluorescent molecular probe, in particular to the preparation and application of a rhodamine B derivative. Background technique

[0002] In the reported aluminum ion fluorescent probes, most of the fluorescence peaks are at short wavelengths, which cannot be observed by naked eyes (F.Dai, F.Liu, Q.Luo, C.W.YuandQ.L.Huang, International Journal of Science and Technology, 2014, 3, 1 -4.; J. Zhang, N. Li, F. Dai, Q. Luo and Y. X. Ji, Sensors & Transdusors, 2015, 186, 125-128.; S. B. Wen, Y. X. Ji, C. X. Guan, and Q. Y. Fu, Sensors & Transdusors, 2015,190,31-34.), this pair of Al 3+ The detection has brought great influence and inconvenience. Especially due to the influence of the coordination properties of aluminum ions themselves, Al 3+ There are fewer studies on probes (A. Banerjee, A. Sahana, S. Das, S. Lohar, S. Guha, B. Sarkar, S. K. Mukhopadhyay, A. K. Mukherjee and D. Das, Analyst, 2012, 139, 2166-2175.) .

[0003] R...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More