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A kind of traditional Chinese medicine for treating cerebral apoplexy and its preparation process

A technology of stroke and traditional Chinese medicine, which is applied in the direction of blood diseases, extracellular fluid diseases, medical preparations containing active ingredients, etc., can solve the problems of patients and family members unprepared

Active Publication Date: 2016-12-21
吉林省长源药业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

Once it happens, patients and family members are often caught off guard

Method used

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  • A kind of traditional Chinese medicine for treating cerebral apoplexy and its preparation process
  • A kind of traditional Chinese medicine for treating cerebral apoplexy and its preparation process
  • A kind of traditional Chinese medicine for treating cerebral apoplexy and its preparation process

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0048] Ingredients: Panax notoginseng 150g; Pueraria root 120g; Radix Paeoniae Rubra 100g; Safflower 100g; Peach kernel 100g; Herb 100g; Blood 80g; Sappan 100g; Chuanxiong 80g; Dilong 50g; Leech 50g and Achyranthes bidentata 50g. The impurities of each medicinal material are removed, washed and dried, and the notoginseng and dried blood are crushed into superfine powder.

[0049] Water extraction and alcohol sinking: add Pueraria root, red peony root, safflower, peach kernel, scorpion grass, sumac, Chuanxiong, earthworm, leech, and achyranthes bidentata to boil 3 times, add 12 times the amount of water for the first time, and boil for 1 hour , add 6 times of water for the second time, decoct for 4 hours, add 10 times of water for the third time, decoct for 2 hours, combine the filtrate, then filter, concentrate the filtrate to a clear paste with a relative density of 1.08 at 50 ° C, add ethanol to make The alcohol content reaches 65%, stir well, stand for 3 days (4°C), filter,...

Embodiment 2

[0052] Ingredients: Panax notoginseng 250g; Pueraria root 240g; Radix Paeoniae Rubra 200g; Safflower 200g; Peach kernel 200g; Herb 200g; Blood 160g; Sappan 200g; Chuanxiong 160g; Dilong 100g; Leech 100g; Achyranthes bidentata 100g.

[0053] Water extraction and alcohol sinking: add Pueraria root, red peony root, safflower, peach kernel, scorpion grass, sumac, chuanxiong, earthworm, leech, and achyranthes bidentata to decoct 3 times, add 6 times the amount of water for the first time, and decoct for 4 hours , add 12 times the amount of water for the second time, decoct for 1 hour, add 8 times the amount of water for the third time, decoct for 3 hours, combine the filtrate, then filter, concentrate the filtrate to a clear paste with a relative density of 1.20 at 50 ° C, add ethanol to make The alcohol content reaches 75%, stir well, stand for 2 days (4°C), filter, recover ethanol until it has no alcohol smell, and concentrate to a thick paste with a relative density of 1.35 at 80...

Embodiment 3

[0056] Ingredients: Panax notoginseng 75g; Pueraria root 60g; Radix Paeoniae Rubra 50g; Safflower 50g; Peach kernel 50g; Herba scutellaria 50g; Dried blood 40g; Sappan 50g; Ligusticum chuanxiong 40g; Dilong 25g; Leech 25g; Achyranthes bidentata 25g.

[0057] Water extraction and alcohol sinking: add Pueraria root, red peony root, safflower, peach kernel, scorpion grass, sumac, Chuanxiong, earthworm, leech, and Achyranthes bidentata for 3 times, add 8 times the amount of water for the first time, and cook for 3 hours , add 10 times the amount of water for the second time, decoct for 2 hours, add 12 times the amount of water for the third time, decoct for 1 hour, combine the filtrate, then filter, concentrate the filtrate to a clear paste with a relative density of 1.12 at 50 ° C, add ethanol to make The alcohol content reaches 80%, stir well, stand for 1 day (4°C), filter, recover ethanol until there is no alcohol smell, and concentrate to a thick paste with a relative density o...

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Abstract

The invention belongs to the field of traditional Chinese medicines, and in particular relates to a traditional Chinese medicinal composition as well as a preparation method and an application thereof. The traditional Chinese medicinal composition is prepared from pseudo-ginseng, radix puerariae, radix paeoniae rubra, safflower carthamus, peach kernels, herba siegesbeckiae, dragon's blood, hematoxylon, rhizoma chuanxiong, earthworm, leech and radix achyranthis bidentatae. The preliminary pharmacodynamics study proves that the traditional Chinese medicinal composition and a medicine provided by the invention have obvious antithrombus effects (P is smaller than 0.05) in the aspects of prolonging the in-vivo thrombogenesis time, reducing the in-vitro thrombus wet weight and dry weight, and inhibiting the platelet aggregation effect, and therefore, the traditional Chinese medicinal composition has an obvious antithrombus curative effect (P is smaller than 0.05).

Description

technical field [0001] The invention relates to the field of traditional Chinese medicines, in particular to a traditional Chinese medicine for treating cerebral apoplexy and a preparation process thereof. Background technique [0002] Stroke, also known as cerebrovascular accident and cerebral apoplexy, is a sudden-onset cerebral blood circulation disorder and the most serious complication of cerebrovascular diseases, including cerebral thrombosis and cerebral hemorrhage, with high morbidity and disability The "four highs" are characterized by high mortality rate, high mortality rate and high recurrence rate. Arteriosclerosis is the main cause, and most of the patients are middle-aged and elderly people over 40 years old; however, in recent years, young patients in their 20s and 30s are increasing, and the youngest patient is only 7 years old, and most of them end up with cerebral hemorrhage and cerebral thrombosis. It is the disease with the highest death rate and the hig...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/896A61P7/02A61K35/62
CPCA61K9/1652A61K9/2059A61K9/4866A61K35/62A61K36/21A61K36/236A61K36/258A61K36/28A61K36/286A61K36/48A61K36/488A61K36/65A61K36/71A61K36/736A61K36/889A61K36/896A61K2300/00
Inventor 宋文慧
Owner 吉林省长源药业有限公司
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