Chinese medicine composition for treating drug-induced pulmonary fibrosis and preparation thereof

A technology for pulmonary fibrosis and drugs for the treatment of pulmonary fibrosis, which is applied in the directions of drug combinations, medical preparations with non-active ingredients, and medical preparations containing active ingredients, etc. High content of substances and the effect of inhibiting toxic absorption

Inactive Publication Date: 2016-03-23
王海文
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, glucocorticoids are often used in the treatment, which can have a certain effect, but the side effects are large, which brings inconvenience to the patient's body.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0010] Embodiment 1: a kind of Chinese medicine composition for the treatment of drug-induced pulmonary fibrosis is characterized in that the raw materials are weighed according to the following total parts: Polygonatum 9 parts, Radix Astragali 9 parts, Cistanche 9 parts, Orchid Butterfly 3 parts, Nine 9 parts of Acorus iris, 9 parts of Guazijin, 9 parts of Trichosanthes, 9 parts of Hedyotis diffusa, 9 parts of Radix Radix, 9 parts of Dilong, 9 parts of Cornus officinalis, and 9 parts of Myrobalan. The method of preparation is the same as above to obtain 100 parts of liquid extract.

Embodiment 2

[0011] Embodiment 2: a kind of Chinese medicine composition for the treatment of drug-induced pulmonary fibrosis is characterized in that the raw materials are weighed according to the following total parts: Polygonatum 6 parts, Radix Astragali 6 parts, Cistanche 9 parts, Wood Butterfly 1.5 parts, Nine 6 parts of Acorus iris, 6 parts of Guazijin, 6 parts of Trichosanthes, 9 parts of Hedyotis diffusa, 6 parts of Radix Radix, 8 parts of Dilong, 9 parts of Cornus officinalis, and 9 parts of Myrobalan. The preparation method is the same as in Example 1, and 100 parts of liquid extracts are obtained.

[0012] Summary of clinical efficacy:

[0013] 1. This prescription has been widely used clinically for many years, and has treated hundreds of patients with frequent curative effects. Contraindications: Stop using rhubarb for those with spleen and stomach deficiency and loose stools.

[0014] 2. Diagnostic criteria: Pulmonary fibrosis mostly occurs after the application of cytotoxi...

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PUM

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Abstract

The invention relates to a Chinese medicine composition for treating drug-induced pulmonary fibrosis. The Chinese medicine composition is characterized in that by total weight, 6-9 parts of polygonatum sibiricum, 6-9 parts of milkvetch roots, 6-9 parts of cistanche deserticola, 1.5-3 parts of oroxylum indicum, 6-9 parts of lrkutsk anemone rhizome, 6-9 parts of Japanese milkwort herbs, 6-9 parts of trichosanthes kirilowii maxim, 6-9 parts of spreading hedyotis, 6-9 parts of ampelopsis japonica, 6-9 parts of earthworms, 6-9 parts of dogwood and 6-9 parts of fructus terminaliae billericae are weighed. The Chinese medicine composition has the advantages that the content of extract obtained through a preparation technology is high, the effects of detoxification and toxin expelling are achieved, toxicity absorption is restrained, the physiological function of cells is improved, damaged tissue is activated and repaired, and lung discomfort is eliminated; the Chinese medicine composition takes effect fast, and is high in cure rate and small in side effect.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition for treating drug-induced pulmonary fibrosis and its preparation. Background technique [0002] An increasing number of drugs, most commonly cytotoxic drugs, are known to cause disseminated interstitial pneumonia and pulmonary fibrosis. Pulmonary fibrosis can be caused by the use of ergonovine, hydralazine, amiodarone, methotrexate, bleomycin, and the like. The time interval from medication to onset varies, and it can be acute or chronic. Patients feel shortness of breath or pulmonary interstitial inflammation on X-ray chest X-ray. So far, the mechanism of pulmonary fibrosis is still unclear. For example, bleomycin has direct cytotoxicity to lung epithelial cells and endothelial cells, and can cause type II epithelial cell hyperplasia and alveolitis of neutrophils, eosinophils, and macrophages. At present, glucocorticoids are often used in the treatment, which can have a certain eff...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8969A61P11/00A61K35/62
CPCA61K36/8969A61K9/0095A61K35/62A61K36/185A61K36/40A61K36/428A61K36/481A61K36/64A61K36/69A61K36/71A61K36/748A61K36/87A61K47/36A61K2236/333A61K2236/39A61K2236/51
Inventor 王海文宋涛
Owner 王海文
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