Application of macrolides in anti-filovirus infection

A technology of macrolides and filoviruses, which is applied in the field of medicine and can solve the problems that the antiviral effect has not been reported.
CN105477007BActive Publication Date: 2020-02-18INST OF MATERIA MEDICA CHINESE ACAD OF MEDICAL SCI
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
INST OF MATERIA MEDICA CHINESE ACAD OF MEDICAL SCI
Publication Date
2020-02-18

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Abstract

The invention discloses an application of a macrolides medicine to preventing inovirus infection. The invention includes an application of the macrolides medicine to prevent or treat inovirus infection. The medicine has a macrolides structural characteristic and is selected from at least one of azithromycin, telithromycin, clarithromycin, carbomycin A, josamycin, kitasamycin, midecamycin, mikamycin, oleandomycin, spiramycin, troleandomycin, tulathromycin, flurithromycin, tilmicosin, rokitamycin, cethromycin, tacrolimus, pimecrolimus, sirolimus, and amphotericin B.
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Description

technical field

[0001] The invention relates to the application of macrolide drugs in anti-filovirus infection, and belongs to the technical field of medicine. Background technique

[0002] Filoviridae, also known as filoviruses, has only one genus of viruses, the genus Filovirus. Filovirus is an enveloped virus with a filamentous appearance and its genome is a single-stranded negative-sense RNA. This genus includes two viruses, namely Ebola virus (EBOV) and Marburg virus (Marburg virus, MBV). ), both of these viruses are controlled viruses, which need to be completed in a biosafety level 4 (P-4) laboratory [Centers for Disease Control and Prevention / National Institutes of Health.Biosafety in Microbiological and Biomedical Laboratories.4th ed.Washington, DC : U.S. Department of Health and Human Services, U.S. Government Printing Office; 1999. DHHS Publication CDC 93-8395.]. Ebola hemorrhagic fever (Ebola hemorrhagic fever, EHF) is caused by Ebola virus, is a serious threat...

Claims

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