Penetration enhancer for cosmetics
A technology for cosmetics and penetration enhancers, applied in the field of penetration enhancers for cosmetics, can solve the problems of short onset time, long penetration time lag, etc., and achieves short onset time, reduced penetration time delay, and high penetration efficiency. Effect
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[0027] The preparation method of penetration enhancer for cosmetics:
[0028] 1) Take a certain amount of natural Chinese herbal extract components and add them to 0.05-0.07mol / L citrate buffer (pH7.5-8.5), and then set the molar ratio of natural Chinese herbal extract components to dextran monomer at 5 : 1-10: 1 Add dextran, control the temperature of 60-70° C. to stir and react for 7-10 hours, freeze and dry the reaction solution, and obtain the natural Chinese herbal medicine extract component modified by dextran.
[0029] 2) Add 60-80% natural Chinese herbal medicine extract components and 20-40% HEPES into the container by weight percentage, stir evenly, and prepare the cosmetic penetration enhancer of the present application.
[0030] testing method: The penetration enhancing effect of penetration enhancer was investigated by Franze diffusion cell method.
[0031] Functional ingredients: sodium hyaluronate (HA), molecular weight 600,000-700,000.
[0032] Experiment...
Embodiment 1-5
[0044] First prepare the penetration enhancer according to the preparation method of the penetration enhancer for cosmetics and the formula in Table 1, and add it to the cosmetic at a ratio of 0.02% to 0.5%, and compare it with the cosmetic without any penetration enhancer (blank control group) Compared with the cosmetics added with 2% azone penetration enhancer (azone penetration enhancer group), the penetration enhancement effect of the cosmetics was investigated by the Franze diffusion cell method, and the test results are shown in Table 2.
[0045] Table 2 Comparative test results
[0046]
[0047] Note: * indicates that the accumulated penetration amount cannot be detected.
[0048]It can be seen from Table 2 that compared with the blank control group and the azone penetration enhancer group, the cosmetics added with natural Chinese herbal medicine penetration enhancer had a shorter onset time, and obvious penetration enhancement effect had been produced in 10 minutes....
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