Cerebrovascular disease prevention and treatment pharmaceutical preparation and preparation method thereof

Abstract

The present invention relates to a cerebrovascular disease prevention and treatment pharmaceutical preparation and a preparation method thereof, wherein gastrodia elata, processed eucommia ulmoides, processed radix aconiti kusnezoffii, processed radix aconiti lateralis preparata, radix angelicae pubescentis, ligusticum sinense oliv, radix scrophulariae, angelica sinensis, rehmannia glutinosa, cyathula officinalis kuan, viscum coloratum, and notopterygium incisum are subjected to extraction refining, and a proper amount of an auxiliary material is added to prepare the cerebrovascular disease prevention and treatment pharmaceutical preparation. According to the present invention, the cerebrovascular disease prevention and treatment pharmaceutical preparation has effects of liver pacifying, endogenous wind stopping, blood circulation activation, cold expelling, tendon relaxing and pain stopping, and mainly used for treatments of ischemic cerebrovascular diseases caused by hyperactive liver yang causing wind and meridian stagnation caused by cold-damp, wherein the symptoms comprise tendon and vessel pain, numbness of limbs, difficult walking, lumbar and leg aching pain, headache, dizziness, sluggish complexion, slurred speech and the like; and compared with the preparation in the prior art, the preparation of the present invention is the active site extraction preparation, and has characteristics of high purity, low taking dose, high bioavailability, stable quality, excellent treatment effect, low toxicity, and good safety.

Description

Technical field: [0001] The invention relates to a pharmaceutical preparation for preventing and treating cerebrovascular diseases and a preparation method thereof, belonging to the technical field of medicines. Background technique: [0002] Cerebrovascular disease refers to brain tissue lesions caused by various etiologies leading to cerebrovascular damage. Acute cerebrovascular disease with acute onset and rapid brain dysfunction is called acute cerebrovascular disease, also known as cerebrovascular accident, cerebral apoplexy or cerebral apoplexy. It has the characteristics of high incidence, high disability rate and high recurrence rate. People are common and frequently-occurring disease. Cerebrovascular diseases, cardiovascular diseases and malignant tumors occupy the top three causes of human natural death. The incidence of cerebrovascular diseases varies with different regions, ethnic groups, and living habits. In my country, the incidence of cerebrovascular diseas...

AI Technical Summary

Problems solved by technology

Years of clinical application show that the original dosage form has good clinical curative effect, but there are the following deficiencies: (1) The original dosage form is completely expressed in terms of traditional Chinese medicine, and does not combine Western medicine to explain what disease to treat, which has brought certain limitations to the promotion of the drug, and clinical practice It is used in the treatment of ischemic stroke, cerebral thrombosis, cerebral arteriosclerosis, cerebral insufficiency, high blood pressure, etc. caused by muscle pain, numbness of limbs, inconvenient walking, sore waist and legs, headache and dizziness; (2) original dosage form The preparation process is rough and the technical content is not high, which is mainly reflected in: ① the original preparations contain a large amount of volatile substances in the four medicinal materials of lovage, ligusticum, angelica, and notopterygium. loss, the quality and curative effect of the drug cannot be guaranteed; ②The original preparation is only crudely extracted and processed, which contains a large amount of impurities, which brings the following problems to the preparation: First, the large amount of impurities makes the preparation dosage large, which brings inconvenience to the medication; Because some impurities have strong water absorption, it is easy to make the preparation absorb moisture and deteriorate, and the quality and curative effect of the drug cannot be guaranteed; ③ Gastrodia elata is directly crushed in the original preparation to make the preparation, which brings the following problems to the preparation: First, it contains a large amount of impurities to make the preparation The amount is large, which brings inconvenience to the medication. The second is that the raw powder of the medicinal material is directly used as medicine, and the active substance cannot be completely absorbed, resulting in low bioavailability. The drug works slowly

Throughout the entire preparation process, the quality and curative effect of the preparation cannot be well reflected

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