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Traditional Chinese medicine preparation for treating periodic extrauterine hemorrhage with syndrome of heat stagnated in liver channels

A traditional Chinese medicine preparation and a heat-suppressing type technology, which is applied in the field of traditional Chinese medicine preparations for the treatment of periodic extrauterine bleeding of the liver meridian heat-suppressing type, can solve problems such as unsatisfactory effects, and achieve the effects of remarkable effect, good safety, and improving epistaxis.

Inactive Publication Date: 2016-06-01
栾凯雍
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

If no obvious local lesions are found, but epistaxis and hematemesis are large, progesterone-only pseudopregnancy therapy or androgen therapy can be used, and some people advocate long-term application of estrogen-progestin cycle therapy, but the effect is not ideal

Method used

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  • Traditional Chinese medicine preparation for treating periodic extrauterine hemorrhage with syndrome of heat stagnated in liver channels

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0058] Embodiment 1 capsule 1

[0059] Take 25g of angelica, 20g of red peony root, 40g of salvia miltiorrhiza, 30g of bupleurum, 20g of poria cocos, 10g of mint, 15g of Moutan cortex, 20g of raw gardenia, 20g of rehmannia root, 25g of skullcap, 35g of gentian, 15g of raw licorice, 20g of coriander root, 15g madder, 20g spatholobus, 20g anemarrhena, 15g raw gypsum, 10g Oujie charcoal, 20g Agrimony, 15g mulberry, 15g Nepeta charcoal, 20g Achyranthes bidentata and 10g antelope horn, washed separately, crushed, mixed together, Add 4kg of ethanol with an alcohol concentration of 90%, heat and reflux for extraction 3 times, each time for 2 hours, and combine the extracts; the obtained extracts recover ethanol under reduced pressure, concentrate to 0.5g crude drug / ml, adjust the pH to 3 with acid, and let it cool , filtered, the volume of resin on the filtrate is equivalent to the macroporous resin column with 3 times the volume of crude drug liquid, first wash with 1 times the colu...

Embodiment 2

[0060] Embodiment 2 Capsule 2

[0061] Take 25g of angelica, 15g of red peony root, 35g of salvia miltiorrhiza, 30g of bupleurum, 15g of poria cocos, 10g of mint, 15g of Moutan cortex, 15g of raw gardenia, 20g of rehmannia root, 25g of scutellaria baicalensis, 30g of gentian, 15g of raw licorice, 20g of Imperata rhizome, 15g Rubia, 15g Caulis Spatholobus, 20g Anemarrhena, 10g raw gypsum, 5g Oujie charcoal, 15g Agrimony, 15g mulberry, 15g Nepeta charcoal, 15g Achyranthes bidentata and 5g antelope horn, washed separately, crushed, mixed together, Add 4kg of ethanol with an alcohol concentration of 90%, heat and reflux for extraction 3 times, each time for 2 hours, and combine the extracts; the obtained extracts recover ethanol under reduced pressure, concentrate to 0.5g crude drug / ml, adjust the pH to 3 with acid, and let it cool , filtered, the volume of resin on the filtrate is equivalent to the macroporous resin column with 3 times the volume of crude drug liquid, first wash ...

Embodiment 3

[0062] Embodiment 3 Capsule 3

[0063] Take 30g of angelica, 20g of red peony root, 40g of salvia miltiorrhiza, 35g of Bupleurum bupleuri, 20g of poria cocos, 15g of mint, 20g of Moutan bark, 20g of raw gardenia, 25g of rehmannia root, 30g of scutellaria baicalensis, 35g of gentian, 20g of raw licorice, 25g of coriander root, 20g Rubia, 20g Caulis Spatholobus, 25g Anemarrhena, 15g raw gypsum, 10g Oujie charcoal, 20g Agrimony, 20g mulberry, 20g Nepeta charcoal, 20g Achyranthes bidentata and 10g antelope horn, washed separately, crushed, mixed together, Add 4kg of ethanol with an alcohol concentration of 90%, heat and reflux for extraction 3 times, each time for 2 hours, and combine the extracts; the obtained extracts recover ethanol under reduced pressure, concentrate to 0.5g crude drug / ml, adjust the pH to 3 with acid, and let it cool , filtered, the volume of resin on the filtrate is equivalent to the macroporous resin column with 3 times the volume of crude drug liquid, firs...

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Abstract

The invention provides a traditional Chinese medicine preparation for treating periodic extrauterine hemorrhage with syndrome of heat stagnated in liver channels. The traditional Chinese medicine preparation is prepared from Radix Angelicae Sinensis, Radix Paeoniae Rubra, Radix Salviae Miltiorrhizae, Radix Bupleuri, Poria, Herba Menthae, Cortex Moutan, Fructus Gardeniae (raw), Radix Rehmanniae (raw), Radix Scutellariae, Radix Gentianae, Radix Glycyrrhizae (raw), Rhizoma Imperatae, Radix Rubiae, Caulis Spatholobi, Rhizoma Anemarrhenae, Gypsum Fibrosum (raw), Nodus Nelumbinis Rhizomatis(carbonized), Herba Agrimoniae, Fructus Mori, Herba Schizonepetae(carbonized), Radix Cyathulae and Cornu Saigae Tataricae. The traditional Chinese medicine preparation has significant effect in reducing periodic extrauterine hemorrhage such as epistaxis and bleeding gums, is more effective than western medicine, has high safety, and is suitable for clinical promotion and application.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine, in particular to a traditional Chinese medicine preparation for treating periodic extrauterine bleeding of liver meridian stagnant heat type. Background technique [0002] During the menstrual period, bleeding occurs in parts other than the uterus, such as the nasal mucosa, stomach, intestines, lungs, and breasts. At this time, the menstruation is less, or even no menstruation, and the amount of epistaxis or vomiting blood can be more or less. It is often accompanied by symptoms such as general malaise, lack of energy, irritability, and distending pain in the lower abdomen. [0003] Most menstrual cramps are caused by endometriosis, and the etiology may be related to abnormal differentiation of visceral epithelium. Blood disease is also one of the factors that cause retrograde menstruation. Menstruation is the main feature of the physiological performance of sexually matur...

Claims

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Application Information

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IPC IPC(8): A61K36/899A61P15/00A61P7/04A61K35/32A61K33/06
CPCA61K36/899A61K9/4825A61K33/06A61K35/32A61K36/076A61K36/21A61K36/232A61K36/233A61K36/484A61K36/486A61K36/515A61K36/534A61K36/537A61K36/538A61K36/539A61K36/605A61K36/62A61K36/65A61K36/71A61K36/73A61K36/74A61K36/744A61K36/804A61K36/8964A61K2236/333A61K2236/39A61K2236/51A61K2236/55A61K2300/00
Inventor 栾凯雍
Owner 栾凯雍