Unlock instant, AI-driven research and patent intelligence for your innovation.

A kind of separation and detection method of bisphenol A

A detection method and bisphenol technology, applied in the field of organic chemistry and analytical chemistry, can solve the problems of incomplete elution of template molecules, low BPA adsorption and adsorption capacity, etc., and achieve the effect of increasing adsorption capacity and specific recognition function

Active Publication Date: 2018-01-23
SOUTH CHINA NORMAL UNIVERSITY
View PDF5 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] However, part of the imprinted sites of magnetic molecularly imprinted polymers is embedded in the polymer body, resulting in incomplete elution of template molecules
Moreover, the molecularly imprinted polymers in the prior art have significantly lower selective adsorption and adsorption capacity for BPA in the water phase, and cannot be used to separate and detect the content of BPA in the water phase.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • A kind of separation and detection method of bisphenol A

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0028] A method for separating and detecting bisphenol A disclosed by the invention comprises the following steps:

[0029] (1) Sample treatment: add acetonitrile to the sample, shake and mix well, centrifuge, and take the supernatant as the sample solution to be tested.

[0030] (2) Add the magnetic molecularly imprinted polymer into the liquid to be tested, shake for 20-120 min, and magnetically separate the magnetically imprinted polymer.

[0031] (3) Eluting the bisphenol A in the magnetic molecularly imprinted polymer with a certain volume of elution solvent, and collecting the eluate.

[0032] (4) The concentration of bisphenol A in the eluate was determined by HPLC / UV.

[0033] In this embodiment, pure milk samples are taken as an example. In a 15 mL centrifuge tube, add 5 mL of pure milk followed by 5 mL of acetonitrile. After shaking for 1-2 minutes, the mixture was centrifuged at a speed of 4000 r / min for 15-30 minutes, and the supernatant was taken as the liquid ...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses a method for separating and detecting bisphenol A, which comprises the following steps: (1) adding acetonitrile to the sample, shaking and mixing, centrifuging, and taking the supernatant as the sample liquid to be tested; (2) adding acetonitrile to the sample to be tested Add magnetic molecularly imprinted polymers into the solution, shake for 20 to 120 minutes, and magnetically separate the magnetic molecularly imprinted polymers; (3) Elute the bisphenol A in the magnetic molecularly imprinted polymers with a certain volume of elution solvent, and collect the eluate (4) measure the concentration of bisphenol A in the eluent with HPLC / UV; Described magnetic molecular imprinting polymer is to take bisphenol A as template, 4-vinylpyridine and alkylated β-cyclodextrin as Two functional monomers are prepared by RAFT. The present invention adopts magnetic surface molecularly imprinted polymers to avoid embedding of imprinted sites in polymers; the synergistic effect of two functional monomers and bisphenol A greatly increases the adsorption capacity and specific recognition function of molecularly imprinted polymers on the surface of magnetic microspheres .

Description

technical field [0001] The invention relates to the fields of organic chemistry and analytical chemistry, in particular to a method for separating and detecting bisphenol A. Background technique [0002] Bisphenol A (BPA) is an important organic chemical raw material, which has been mass-produced and widely used, and has been detected in water, sediment, soil, atmospheric environment and organisms. Trace or even trace amounts of BPA can cause adverse effects on animal physiological conditions, reproductive system and fetal development. At present, BPA analysis methods mainly include high performance liquid chromatography (HPLC), gas chromatography-mass spectrometry (GC-MS) and capillary electrophoresis (CE). However, the content of BPA in actual samples is low, and the sample substrate is complex, resulting in serious interference, which is difficult to detect directly. [0003] Bisphenol A is usually at trace levels in environmental media, and environmental samples usuall...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Patents(China)
IPC IPC(8): G01N30/02
CPCG01N30/02G01N2030/027
Inventor 梁勇
Owner SOUTH CHINA NORMAL UNIVERSITY