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Compound phellinus igniarius medicine for treating hand-foot-and-mouth disease and preparation method thereof

A compound phellinus and hand, foot and mouth disease technology, applied to medical preparations containing active ingredients, antiviral agents, pharmaceutical formulas, etc., can solve the problem of easy mutation of antigens and achieve strong anti-enterovirus 71 effects

Inactive Publication Date: 2016-07-06
FUJIAN AGRI & FORESTRY UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, due to the large number of serotypes of the EV71 virus, the antigen is prone to mutation, and it is imperative to find effective anti-EV71 and drugs for the treatment of hand, foot and mouth disease.

Method used

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  • Compound phellinus igniarius medicine for treating hand-foot-and-mouth disease and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] A compound Phellinus medicament for treating hand, foot and mouth disease, in parts by weight, the raw materials of the compound Phellinus medicament include: 15 parts of Phellinus polysaccharide and 2 parts of a compound Chinese medicine composition; the preparation method of the compound Chinese medicine composition Method: dry licorice, isatidis and forsythia in an oven at 60°C, crush them and pass through a 50-mesh sieve, take 10 parts of licorice powder, 10 parts of isatidis powder and 5 parts of forsythia powder and mix them evenly, put them in a casserole and add 1000 parts of distilled water Soak each portion for 30 minutes, heat and boil on high heat, then change to simmer for 2 hours, filter and cool, centrifuge at 3000r / min, concentrate, and freeze-dry to obtain a Chinese medicine compound composition.

[0024] The preparation method of described Phellinus polysaccharide, comprises the following steps:

[0025] (1) Phellinus strains are inoculated on the soli...

Embodiment 2

[0036] A compound Phellinus Phellinus medicament for treating hand-foot-mouth disease, in parts by weight, the raw materials of the compound Phellinus Phellinus medicament include: 25 parts of Phellinus polysaccharide and 6 parts of Chinese medicine compound composition; the preparation method of the Chinese medicine compound composition Method: dry licorice, isatidis and forsythia in an oven at 65°C, crush them and pass through an 80-mesh sieve, take 15 parts of licorice powder, 20 parts of isatidis powder and 10 parts of forsythia powder and mix them evenly, put them in a casserole and add 1000 parts of distilled water Soak each portion for 30 minutes, heat and boil on high heat, then change to simmer for 2 hours, filter and cool, centrifuge at 3500r / min, concentrate, and freeze-dry to obtain a Chinese medicine compound composition.

[0037] The preparation method of described Phellinus polysaccharide, comprises the following steps:

[0038] (1) Phellinus strains are inocula...

Embodiment 3

[0049] A compound Phellinus Phellinus medicament for treating hand, foot and mouth disease, in parts by weight, the raw materials of the compound Phellinus Phellinus medicament comprising: 20 parts of Phellinus polysaccharide and 4 parts of a compound Chinese medicine composition; the preparation method of the compound Chinese medicine composition Method: dry licorice, isatidis and forsythia in an oven at 62°C, crush them and pass through a 65-mesh sieve, take 12 parts of licorice powder, 15 parts of isatid root powder and 8 parts of forsythia powder and mix them evenly, put them in a casserole and add 1000 parts of distilled water Soak each portion for 25 minutes, heat and boil on high heat, then change to simmer for 1.5 hours, filter and cool, centrifuge at 3300r / min, concentrate, and freeze-dry to obtain a Chinese medicine compound composition.

[0050] The preparation method of described Phellinus polysaccharide, comprises the following steps:

[0051] (1) Phellinus strain...

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Abstract

The invention discloses a compound phellinus igniarius medicine for treating hand-foot-and-mouth disease and a preparation method thereof, and belongs to the technical field of medical health products. The preparation method comprises: inoculating a phellinus igniarius strain to a solid fermentation culture medium, performing fermentation to obtain phellinus igniarius mycelia, then performing leaching, rotary evaporation, centrifugation, re-dissolution, protein removal, pigment removal and dialysis to prepare phellinus igniarius polysaccharides from the phellinus igniarius mycelia, and then matching the phellinus igniarius polysaccharides with extracts of licorice root, weeping forsythia capsule and indigowoad root to prepare a compound medicine by mixing. The prepared compound phellinus igniarius polysaccharide medicine can effectively resist an enteric virus disease of type 71, and has a relatively good effect of treating the hand-foot-and-mouth disease.

Description

technical field [0001] The invention belongs to the technical field of medicine and health care products, and in particular relates to a compound phellinus medicament for treating hand-foot-mouth disease and a preparation method thereof. Background technique [0002] Hand, foot and mouth disease is an acute infectious disease in children clinically characterized by maculopapules and herpes on the hands, feet, mouth, buttocks, and is more common in infants and young children under 3 years old. Enterovirus 71 (EV71) is one of the most important pathogens causing hand, foot and mouth disease. At present, the main prevention and treatment methods for EV71 virus infection include vaccine development, immunoglobulin therapy, and antiviral chemical synthesis drugs. However, due to the large number of serotypes of EV71 virus, the antigen is easily mutated, and it is imperative to find effective anti-EV71 and therapeutic drugs for hand, foot and mouth disease. [0003] Phellinus is ...

Claims

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Application Information

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IPC IPC(8): A61K36/634A61P31/14A61K31/715
CPCA61K36/634A61K31/715A61K36/07A61K36/195A61K36/315A61K36/484A61K2236/331A61K2236/51A61K2236/53A61K2300/00
Inventor 赵超陈玉青刘斌高路营
Owner FUJIAN AGRI & FORESTRY UNIV
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