Biodegradable medical abdominal surgical suture material

Abstract

The invention provides a biodegradable medical abdominal surgical suture material. The biodegradable medical abdominal surgical suture material, a composite biodegradable material, consists of a cylindrical core layer, a middle layer wrapping the core layer and a cover layer wrapping the middle layer, wherein the core layer is selected from polyglycolic acid, polylactic acid, polycrylactone or a copolymer thereof, the middle layer is selected from carboxymethyl chitosan, chitosan fibers or collagenous fibers, and the cover layer is selected from polyglycolic acid, polylactic acid, polycrylactone or a copolymer thereof. The biodegradable medical abdominal surgical suture material has the advantages of no toxicity, no irritation, biocompatibility and capability of avoiding causing inflammatory reaction since a degradation product of a surgical suture is finally decomposed into carbon dioxide and water which are free of toxicity.

Description

Technical field [0001] The invention relates to a biodegradable medical abdominal surgical suture material, belonging to the technical field of biomedical material production. Background technique [0002] Biodegradable materials in medicine refer to a class of biological materials with special properties that are used for surgical repair, physical therapy rehabilitation, diagnosis, and treatment of patients. They can be degraded and absorbed in the organism without adversely affecting human tissues. . With the development of tissue engineering technology, biodegradable materials have been rapidly developed, and their applications involve almost all non-permanent implantable devices, including controlled drug release carriers, surgical sutures, surgical care devices, hemostatic equipment, and surgical prevention. Adhesion membrane, tissue and cell engineering, etc. [0003] Biodegradable materials include: 1) Natural degradable polymer materials: mainly collagen, gelatin, chitosa...

AI Technical Summary

Problems solved by technology

2) Synthetic degradable polymer materials: it is the main research object of biomaterials for tissue engineering, among which polylactide series materials are the main ones; the degradation speed and strength of this kind of materials can be adjusted, and it is easy to shape and build high porosity Three-dimensional scaffold; the essential defect of this kind of material is that the concentrated release of its degradation products is prone to inflammation, which will make the culture environment too acidic

Such materials have weak affinity to cells and often require physical methods or the addition of certain factors to adhere to cells