Medicine for external use with dual effects of analgesia and antibacterial, preparation and preparation method thereof

Abstract

The invention discloses an external-use drug and preparation with analgesic and antibacterial effect and a preparation method thereof. The external-use drug comprises a component A like silver sulfadiazine, a component B like zinc sulfadiazine and an analgesic component like lidocaine. Excipients of the preparation include Carbomer, glycerin, triethanolamine and water. The preparation method includes: adding water into Carbomer for swelling, and adding triethanolamine to adjust pH to obtain transparent colloid; adding glycerin dispersed with the components A and B into the transparent colloid to obtain milky colloid; using water to disperse and dissolve the analgesic component, adding into the milky colloid, using water to adjust water content, and stirring well. The external-used drug and preparation has the analgesic and antibacterial effect, wound healing time can be shortened remarkably, and the preparation method is simple, convenient, economical and wide in application prospect.

Description

technical field [0001] The invention belongs to the technical field of medicines, and in particular relates to a compound medicine with dual effects of analgesia and antibacterial and a preparation method of a gel thereof. Background technique [0002] Trauma problems such as lacerations, abrasions, burns and scalds caused by various reasons have a high frequency of occurrence. Skin damage can easily lead to infection of the injured part, and exposure of wound facial nerves can easily cause severe pain. The dual threat of injury and infection will seriously affect the patient's health. In good health, if the treatment is not timely, it will often induce insomnia, autonomic dysfunction, limited exercise capacity, chronic pain and depression, etc., which will seriously affect the quality of life of the patient. [0003] At present, most of the topical medicines for treating wounds and burns are single-function (anti-infection or pain-relieving) preparations, which are difficul...

AI Technical Summary

Problems solved by technology

In superficial skin injuries, because the nerve endings are exposed to stimulation, the wound will cause severe pain. In addition, if the wound bleeding is not treated in time, it will also bring inconvenience to the patient's daily activities

Current topical drugs for the treatment of superficial skin lesions, such as silver sulfadiazine, povidone-iodine ointment, and Yunnan Baiyao, are all single-function (anti-infection or pain-relieving) preparations, which are difficult to meet the treatment needs

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