Liver fat qualitative measurement method based on ultrasonic attenuation coefficient

A technology of attenuation coefficient and quantitative measurement, which is applied in ultrasonic/acoustic/infrasonic diagnosis, ultrasonic diagnosis, infrasonic diagnosis, etc., to achieve high precision, simple calculation, and accurate calculation results

Inactive Publication Date: 2016-09-07
BEIJING UNIV OF TECH
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Problems solved by technology

The above method is easily affected by the scattering factors in the signal propagation process and the factors of the ultrasonic instrument itself

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  • Liver fat qualitative measurement method based on ultrasonic attenuation coefficient
  • Liver fat qualitative measurement method based on ultrasonic attenuation coefficient
  • Liver fat qualitative measurement method based on ultrasonic attenuation coefficient

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Embodiment Construction

[0038] The data used for the verification of the ultrasonic attenuation coefficient algorithm in the present invention are all obtained from scanning the liver tissue of patients with clinically different degrees of fatty liver with ultrasonic probes of different frequencies. The specific implementation steps are as follows:

[0039] 1. Measure the liver fat content of several patients with different degrees of fatty liver clinically or in experiments, and use ultrasound probes of different frequencies to scan the patient's liver tissue to obtain ultrasound echo signals data1 and data2.

[0040] 2. Detect the ultrasonic echo data data1 and the ultrasonic echo data data2 to obtain the detection signal

[0041] env_data1 and env_data2, and average mean_data1 and mean_data2 for each pixel.

[0042] (1) Detection process (see the accompanying drawings in the manual figure 2 ): Hilbert transform is performed on the ultrasonic echo signals data1 and data2, and the absolute values...

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Abstract

A liver fat qualitative measurement method based on an ultrasonic attenuation coefficient belongs to technical field of signal processing and liver fat attenuation coefficients. The method comprises the steps of: measuring the liver fat content of fatty liver patients at different stages; carrying out scanning to acquire ultrasonic echo signals at different frequencies, i.e. f1 and f2; performing detection on the ultrasonic echo signals by using Hilbert transform; performing time-frequency analysis on the detected signals by using short-time Fourier transform; calculating an average of amplitudes corresponding to different frequencies at each sampling moment; performing logarithm transform on the average at each sampling point; then making a different between two sets of data corresponding points; performing linear fitting on 50 successive points to obtain a straight line slope; and finally obtaining an attenuation coefficient of the corresponding points. The method can be used for performing real-time and precise attenuation coefficient calculation on liver tissues; and eventually, a model is established by means of a corresponding relationship between the liver fat content and the liver ultrasonic attenuation coefficient, and the liver fat content is estimated by calculating the ultrasonic attenuation coefficient of the liver, so as to realize non-invasive measurement of the liver fat content.

Description

technical field [0001] The invention belongs to the technical field of signal processing and liver attenuation coefficient, and in particular relates to a new method for calculating the ultrasonic attenuation coefficient of liver tissue, which is based on the processing of ultrasonic echo signals collected at different frequencies f1 and f2 (the center frequency of an ultrasonic probe) to eliminate the The ultrasound system itself affects the calculation results and is the key technology for quantitative measurement of liver fat. Background technique [0002] Fatty liver is a disease caused by excessive accumulation of fat in liver cells due to various reasons, and it is the second largest liver disease after viral hepatitis. Fatty liver is a reversible disease, and early diagnosis and treatment can often return to normal. Currently, the clinical techniques for detecting liver lesions include ultrasound imaging and computed tomography (CT). Traditional ultrasound imaging c...

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G06F19/00A61B8/00
CPCA61B8/00A61B8/5207G16H50/50
Inventor 吴水才王月周著黄
Owner BEIJING UNIV OF TECH
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