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Sample transfer box

A technology of sample transfer and sample tank, which is applied to the types of packaging items, impact-sensitive items, containers, etc., can solve the problems of incubation and incubation experiment operation requirements, difficulty in moving, and affecting experimental results, etc., to prevent drug precipitation and quality Concentration changes, prevent heat loss, and ensure accuracy

Active Publication Date: 2018-07-10
上海市生物医药技术研究院
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] However, the inventors of the present invention have found that common water bath devices are not only large, heavy, and difficult to move, but also cause unnecessary trouble to the asepsis or cleanliness management of cell rooms or animal rooms due to their frequent entry and exit.
The traditional incubator is usually passively insulated by using insulation materials. When the sample is taken out of the water bath and placed in the incubator, the heat exchange that occurs while the sample tube is in contact with the incubator is enough to cause the drug to precipitate and affect the experimental results.
Therefore, the traditional incubator is difficult to meet the transfer requirements of these highly temperature-sensitive samples, and it is also difficult to meet the temporary storage of samples, as well as the operational requirements of incubation and incubation experiments.

Method used

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Experimental program
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Embodiment approach 1

[0026] The first embodiment of the present invention provides a sample transfer box, see figure 1 and figure 2 As shown, it includes a box body 1 , a heating mechanism 2 arranged in the box body 1 , and a support platform 3 arranged in the heating area of ​​the heating mechanism 2 . The support platform 3 is provided with N sample wells 31 for placing the sample tubes 4 , where N is a natural number, and the heating mechanism 2 is used to maintain the temperature of the sample tubes 4 .

[0027] Wherein, the support platform 3 includes a heat conduction plate 32 and a support plate 33 connected to the heat conduction plate 32 through several heat conduction columns 34 . The heat conduction plate 32 is attached to the heating surface of the heating mechanism 2 , the support plate 33 is spaced apart from the heat conduction plate 32 , the sample slots 31 are located on the support plate 33 , and the heat conduction columns 34 are scattered between the sample slots 31 . Compar...

Embodiment approach 2

[0059] The second embodiment of the present invention provides a sample transfer box, the second embodiment is a further improvement of the first embodiment, the main improvement is that, in the second embodiment of the present invention, see image 3 As shown, the supporting plate 33 is provided with a thermal insulation cavity 331 , and the thermal insulation cavity 331 is filled with thermal insulation liquid, which is used to stabilize the temperature of the support platform 3 .

[0060] Wherein, the thermal insulation fluid may be water, heat conduction oil or other substances with large specific heat capacity. Generally speaking, in order to promote heat transfer and speed up the heating efficiency of the supporting plate 33 , the material of the supporting platform 3 can be a metal material with a lower specific heat capacity. Metal materials heat up quickly and dissipate heat quickly, which is not conducive to heat preservation. Therefore, compared with the support pla...

Embodiment approach 3

[0063] The third embodiment of the present invention provides a sample transfer box. The third embodiment is different from the first and second embodiments. The main difference is that in the first and second embodiments of the present invention, The heat conduction plate 32 and the support plate 33 are detachably connected through the heat conduction column 34; and in the third embodiment of the present invention, see Figure 4 As shown, the heat conduction plate 32 and the supporting plate 33 are fixedly connected through the heat conduction column 34 .

[0064] Specifically, in addition to the fixed connection between the heat conduction plate 32 and the support plate 33 through the heat conduction column 34, the heat conduction plate 32 is also provided with a heat conduction cavity 321, and the heat conduction column 34 is provided with a connection cavity 341, the heat conduction cavity 321 and The heat preservation cavity 331 is connected through the connecting cavity ...

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Abstract

The invention relates to the technical field of biochemistry, pharmacy and medicine relative experiments, and discloses a sample transfer box. The sample transfer box comprises a box body, a heating mechanism arranged inside the box body, and a supporting platform arranged in a heating zone of the heating mechanism, wherein N sample slotted holes used for placing sample tubes are arranged on the supporting platform; N is a natural number; and the heating mechanism is used for maintaining the temperature of the sample tubes. According to the sample transfer box, on one hand, the mass concentration change caused by medicine precipitation due to temperature change can be prevented, and the accuracy of experimental results is guaranteed; and on the other hand, great operability, convenience and flexibly are brought to incubation experiments in cell rooms, animal rooms or limited spaces, and the sample transfer box has the advantages that time is saved, effort is saved, and the like, and provides necessary guarantee for the smooth developing of the experiments.

Description

technical field [0001] The invention relates to the experimental fields of biochemistry, pharmacy and medicine, in particular to a sample transfer box. Background technique [0002] In the process of biochemical, pharmaceutical and medical related experiments, the experimental temperature or ambient temperature has a significant impact on some special sample preparation and experimental results. [0003] For example, the equilibrium solubility experiment of drugs is usually carried out in a water bath at 37 degrees Celsius. After the dissolution equilibrium is reached, the sample is taken out of the water bath, and then a series of processing tasks such as centrifugation, suction of supernatant, and sample injection are performed. Since the solubility of the drug is affected by the temperature kinetics, when the temperature decreases, the drug is precipitated from the solvent, causing a change in the mass concentration, which ultimately affects the accuracy of the equilibriu...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): B65D81/18B65D81/24B65D25/10B65D81/05B65D81/38
CPCB65D25/108B65D81/05B65D81/18B65D81/24B65D81/3813B65D2581/051
Inventor 曾佳俸灵林黄婷李芳潘峰朱芷涵普天磊薛嫚陈建兴
Owner 上海市生物医药技术研究院