Brucellosis vaccine needle-free injection system and application

A needle-free injection technology for brucellosis, applied in the needle-free injection brucellosis vaccine system and application field, can solve the problems of increasing the risk of bleeding and infection, affecting the safety of meat consumption, and cumbersome vaccination operations , to achieve the effect of improving immunization efficiency, improving compliance, and reducing the amount of antigen

Inactive Publication Date: 2016-10-12
INNER MONGOLIA HUAXI BIOTECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Vaccination is the main measure to prevent and control brucellosis. At present, the vaccination of brucellosis vaccine is mainly carried out through intramuscular injection, subcutaneous injection, or oral administration. The Danger of Brucella from a Needle Stick Injury
Especially when vaccinating animals, the problems of cumbersome inoculation operations, environmental pollution, and easy cross-contamination caused by traditional needle injections are particularly prominent.
Traditional injection technology requires professionals to operate, which increases labor costs, and the needle pierces the animal body, which increases the risk of bleeding and infection, and the needle breaks in the animal body, which seriously affects the safety of meat consumption.

Method used

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  • Brucellosis vaccine needle-free injection system and application
  • Brucellosis vaccine needle-free injection system and application
  • Brucellosis vaccine needle-free injection system and application

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0057] Embodiment 1, the preparation of needle-free injection ampoule

[0058] The present invention will be described in detail below in conjunction with the accompanying drawings and embodiments.

[0059] Such as figure 1 A. figure 1 As shown in B, the needle-free injection ampoule of prepacked vaccine or medicine provided by the present invention includes a tube body 1, a needle-free syringe joint 2, a power push rod 3, a jetting port 4, a stop rod 5, A sealing cap 6 and a sealing lock block 7; wherein, the tube body 1 is used for pre-filling a fixed and precise dose of vaccine or medicine, the needle-free syringe connector 2 is integrally arranged at one end of the tube body 1, and the power push rod 3 is controlled by the tube body The other end of 1 is slidingly arranged in the tube body 1, and closes the tube body 1; the injection port 4 is set in the needleless syringe joint 2, which has a stop groove 8, and the injection port 4 passes through the stop slot 8 and the...

Embodiment 2

[0070] Embodiment 2, needle-free injection of brucellosis vaccine system and application

[0071] The MIT needle-free injectors in the following examples are products of Jiangsu Chengyu Miite Medical Technology Co., Ltd., product models: MP-0.1 and MG-0.1, and MP-0.1 is specifically used.

[0072] The needle-free injection brucellosis vaccine system of this embodiment includes a needle-free injection ampoule filled with 1 / 5-1 times the standard dose of the brucellosis vaccine and a matching needle-free syringe.

[0073] 1. Exploration of the injection depth of the needle-free brucellosis vaccine system

[0074] Fill the ink aqueous solution instead of the vaccine into the needle-free injection ampoule prepared in Example 1 to obtain the needle-free injection ampoule filled with the ink aqueous solution.

[0075] The aqueous ink solution is to filter the common blue-black ink with a filter membrane with a pore size of 0.22um, collect the filtrate and dilute it with water for i...

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Abstract

The invention discloses a brucellosis vaccine needle-free injection system and application. The brucellosis vaccine needle-free injection system comprises a container filled with a brucellosis vaccine and a readable carrier. Content recorded in the readable carrier includes that needle-free injection dosage of the brucellosis vaccine is not larger than the standard dosage of the brucellosis vaccine. Experiments prove that when a needle-free injection ampoule and a needle-free syringe are combined and used for immunization, the antigen dosage only accounts for part of a traditional intramuscular injection antigen dosage, and the same or better immune effect can be achieved. It is further indicated that a needle-free immune mode is an ideal strategy capable of being selected by the brucellosis immunization vaccine.

Description

technical field [0001] The invention relates to the field of medicine, especially the field of zoonotic infectious diseases. Specifically, it relates to a needle-free injection brucellosis vaccine system and its application, which is suitable for immunization and vaccination of human or veterinary brucellosis vaccines. Background technique [0002] At present, stainless steel injection needles are commonly used at home and abroad to inject drugs or vaccines into humans or animals. As we all know, the injection of needles will bring a lot of inconvenience, and the safety of injection has become a hot issue in clinical operations. Therefore, a drug or vaccination method that can replace the traditional needle injection method was born-needle-free injection. In recent years, needle-free injection technology is in a stage of rapid development, from traditional high-pressure needle-free injection with large trauma to today's low-pressure needle-free injection with small trauma, ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K39/10A61P31/04A61M5/303
CPCA61K39/098A61K2039/545A61M5/283A61M5/3007
Inventor 温丽娟任天宇王林叶王欢孙治华连梦瑶王鋮李敏杨晓岚木其尔
Owner INNER MONGOLIA HUAXI BIOTECH
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