Geometric correction die body and correction method thereof of pinhole SPECT (single-photon emission computed tomography) system
A technology of geometric correction and phantom, applied in the field of medical imaging, can solve the problems of difficulty in grasping the size of point sources, difficulty in making point source houses, affecting the accuracy of correction, etc., and achieves elimination of accumulated errors, strong controllability, and cavity accuracy. high effect
Active Publication Date: 2016-10-26
PEKING UNIV
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Problems solved by technology
However, in practical engineering, since most radioisotope drugs are in a liquid state, it is difficult to make a point source housing, and it is also difficult to grasp the size of the point source produced.
Moreover, the solid point source has a certain volume, and there is an error compared with the ideal point source, which will also be brought into the calibration process and affect the calibration accuracy; the solid liquid point source is not easy to control during the long-term experiment process, and it is easy to volatilize, which brings various inconveniences
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[0029] The present invention will be further elaborated below through specific embodiments in conjunction with the accompanying drawings.
[0030] Such as figure 1 As shown, the SPECT geometric correction phantom of the present embodiment includes: a base body 11 and first to fourth cavities 12-15; four cavities 12-15 in the shape of straight line segments are arranged in the base body 11, where the four cavities are The straight line segments are located on the same plane, the cross-section of each cavity is 0.5mm, and the length is greater than 20mm. One end of the cavity starts on the surface of the substrate, and the other end ends in the substrate; the first cavity 12 is vertical direction, the second to fourth cavities 13-15 are parallel to each other, and the extension lines respectively intersect with the first cavity 12 to form three intersection points as three virtual point sources.
[0031] The pinhole SPECT geometry correction method of the present invention comp...
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Abstract
The invention discloses a geometric correction die body and a correction method thereof of a pinhole SPECT (single-photon emission computed tomography) system. According to the correction die body, a plurality of cavities, in the form of straight line segments, are formed in a substrate; one end of each cavity starts from the surface of the substrate and the other ends in the substrate; the diameter of a cross section of each cavity is greatly less than the length of the cavity; the plurality of cavities are located within a same plane and are mutually free from coincident points, but at least three intersection points are arranged on extension lines of the straight line sections that the various cavities are located; the cavities are fully filled with radioisotope drugs, so that a line source is formed, and the intersection points on the extension lines of the straight line sections, that positions with the maximum concentration are located, in the cavities serve as virtual point sources; the virtual point sources are obtained through randon transformation, so that the locations of point sources are more precise in correction and the calculation of an elliptical orbit is more precise as well; therefore, accumulative errors are eliminated and correction precision is enhanced; and the geometric correction die body and the correction method disclosed by the invention have the characteristics of being simple to operate, strong in controllability, high in cavity precision and the like.
Description
technical field [0001] The invention belongs to medical imaging technology, and in particular relates to a geometric correction phantom of a pinhole SPECT system and a correction method thereof. Background technique [0002] Single-Photon Emission Computed Tomography (Single-Photon Emission Computed Tomography, SPECT) uses radionuclide disappearance technology to detect the rays emitted by radioisotope drugs ingested in organisms, and reconstruct data through reconstruction algorithms to obtain drugs and targeted Molecular distribution and metabolic information. Spatial resolution and sensitivity are important parameters to measure the performance of SPECT detectors. Among them, the spatial resolution will be limited by the pixel size of the detector crystal, and it is difficult to obtain a higher spatial resolution. Using the pinhole collimator, based on the principle of pinhole magnification imaging, the flexible magnification setting can be realized by adjusting the obj...
Claims
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Login to View More IPC IPC(8): A61B6/03A61B6/00
CPCA61B6/037A61B6/582A61B6/584
Inventor 任秋实李素莹杨昆谢肇恒
Owner PEKING UNIV