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Externally applied drug for treating dermatomycoses and application thereof

A technology for fungal skin diseases and external medicines, applied in skin diseases, antifungal agents, medical preparations containing active ingredients, etc., can solve the problems of violent medicine, single curative effect of western medicine, multi-toxicity, etc.

Inactive Publication Date: 2016-10-26
江苏小林制药有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The current western medicines for treating such diseases have a single curative effect, are violent and multi-toxic, and should not be used in excess for a long time for chronic skin diseases

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0016] Take 10 parts of loess, 30 parts of Cnidium chinensis, and 30 parts of white fresh skin, and the three kinds of raw materials are dried and pulverized to 80 mesh respectively. Soak the crushed Fructus Cnidii Fructus Cnidii and Fresh Cortex Dictatori with 5 times the amount of pure water at 30° C. for 7 days, and filter to obtain filtrate 1 for future use. The obtained dregs were soaked in 1 times the amount of 30% glacial acetic acid at 15°C for 7 days, filtered, and the dregs were discarded to obtain filtrate 2. Combine filtrate 1 and filtrate 2, concentrate under reduced pressure to a concentrated solution with a relative density of 1.2-1.3, add crushed loess to the concentrated solution, add 2% activated carbon and 20% glycerol of the above-mentioned semi-finished product quality, and obtain the present invention Chinese medicine for the treatment of fungal skin diseases.

[0017] Apply the medicine on the affected skin, let it stand for 30 minutes, rinse with water...

Embodiment 2

[0019] Take 5 parts of loess, 20 parts of Fructus Cnidii, and 20 parts of white fresh skin. After drying, the three raw materials are pulverized to 80 mesh respectively. Soak the crushed Fructus Cnidii Fructus Cnidii and Fresh Cortex Dictatori with 5 times the amount of pure water at 30° C. for 7 days, and filter to obtain filtrate 1 for future use. The obtained dregs were soaked in 1 times the amount of 30% glacial acetic acid at 15°C for 7 days, filtered, and the dregs were discarded to obtain filtrate 2. Combine filtrate 1 and filtrate 2, concentrate under reduced pressure to a concentrated solution with a relative density of 1.2-1.3, add crushed loess to the concentrated solution, add 3% activated carbon and 20% glycerin of the above-mentioned semi-finished product quality, and obtain the present invention. Chinese medicine for the treatment of fungal skin diseases.

[0020] Apply the medicine on the affected skin, let it stand for 30 minutes, rinse with water, 1-2 times ...

Embodiment 3

[0022] Take 10 parts of loess, 20 parts of Fructus Cnidii, and 20 parts of white fresh skin. The three raw materials are dried and pulverized to 80 mesh respectively. Soak the crushed Fructus Cnidii Fructus Cnidii and Fresh Cortex Dictatori with 5 times the amount of pure water at 30° C. for 7 days, and filter to obtain filtrate 1 for future use. The obtained dregs were soaked in 1 times the amount of 30% glacial acetic acid at 15°C for 7 days, filtered, and the dregs were discarded to obtain filtrate 2. Combine filtrate 1 and filtrate 2, concentrate under reduced pressure to a concentrated solution with a relative density of 1.2-1.3, add crushed loess to the concentrated solution, add 3% activated carbon and 20% glycerin of the above-mentioned semi-finished product quality, and obtain the present invention. Chinese medicine for the treatment of fungal skin diseases.

[0023] Apply the medicine on the affected skin, let it stand for 30 minutes, rinse with water, 1-2 times a d...

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PUM

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Abstract

The invention relates to an externally applied drug for treating dermatomycoses. Application comprises the following steps: (1) preparing materials, and weighing the following raw material medicine in percentage by mass: 5 to 10 parts of loess, 20 to 30 parts of fructus cnidii and 20 to 30 parts of cortex dictamni; (2) respectively smashing the three kinds of raw material medicine to 80 meshes after being dried; (3) soaking the fructus cnidii and the cortex dictamni which are obtained in step (2) by five times of purified water under 30 DEG C for 7 days, and filtering, thus obtaining filter liquid 1 for standby use; (4) soaking residues obtained in step (3) by 30 percent glacial acetic acid under 15 DEG C for 7 days, filtering, and discarding the residues, thus obtaining filter liquid 2; (5) merging the filter liquid 1 and the filter liquid 2, and decompressing and concentrating the merged filter liquid into concentrated liquid of which the relative density is 1.2 to 1.3; (6) adding the loess in the step (1) in the concentrated liquid obtained in step (5), thus obtaining a semi-finished product; adding active carbon of which the mass is 2 to 5 percent of that of the semi-finished product and glycerin of which the mass is 20 to 30 percent of that of the semi-finished product, and uniformly mixing, thus obtaining a finished drug.

Description

technical field [0001] The invention relates to a medicine for skin diseases, in particular to a medicine for external use for treating fungal skin diseases. Background technique [0002] Fungal skin disease refers to a large class of infectious diseases caused by pathogenic fungi on human skin, mucous membranes, hair, nails and other skin appendages. It is contagious and recurrent, and brings a lot of pain to patients. The current Western medicines for treating such diseases have a single curative effect, are violent and multi-toxic, and should not be used in excess for a long time for chronic skin diseases. Contents of the invention [0003] The invention provides an external medicine for treating fungal skin diseases and its application. The preparation method of the traditional Chinese medicine for external use is simple, the treatment effect is good, the toxic and side effects are small, and it is safe and effective. [0004] The technical scheme adopted in the prese...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/75A61P31/10A61P17/00A61K35/02
CPCA61K9/0014A61K35/02A61K36/234A61K36/75A61K2236/333A61K2236/51A61K2300/00
Inventor 王福东孙婕李怀琴钱友
Owner 江苏小林制药有限公司
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