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Extraction process and application of guava active substance

An extraction process and technology of active substances, applied in the field of extraction of guava active substances, can solve the problems of rare chemical components of guava peel, and achieve the effect of simple method

Inactive Publication Date: 2016-11-16
SUN YAT SEN UNIV +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, due to the limitations of the extraction process, studies on the chemical components of guava peel are relatively rare

Method used

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  • Extraction process and application of guava active substance
  • Extraction process and application of guava active substance
  • Extraction process and application of guava active substance

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] The extraction I of embodiment 1, guava active substance

[0027] Accurately weigh 0.5g guava peel, add 2.00mL extract, the extract is 20% (v / v) ethanol aqueous solution. Ultrasound for 30min at 50°C, ultrasonic frequency: 380w. After sonication, centrifuge at 4200 g for 20 min, and collect the supernatant. The supernatant was evaporated to dryness at 4°C, and the mass of the active substance obtained by weighing was: 34 mg.

Embodiment 2

[0028] Embodiment 2, the extraction II of guava active substance

[0029] Accurately weigh 0.5g guava peel, add 5.00mL extract, the extract is 70% (v / v) ethanol aqueous solution. Ultrasonic at 70°C for 20min, ultrasonic frequency: 380w. After sonication, centrifuge at 4200 g for 20 min, and collect the supernatant. The supernatant was evaporated to dryness at 4°C, and the mass of the active substance obtained by weighing was 46 mg.

Embodiment 3

[0030] Embodiment 3, the extraction III of guava active substance

[0031] Accurately weigh 0.5g guava peel, add 5.00mL extract, the extract is 55% (v / v) ethanol aqueous solution. Sonicate at 70°C for 20 minutes, and the ultrasonic frequency is 380w. After sonication, centrifuge at 4200 g for 20 min, and collect the supernatant. The supernatant was evaporated to dryness at 4°C, and the mass of the active substance obtained by weighing was 38 mg.

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Abstract

The invention discloses an extraction process of a guava active substance. The extraction method is simple and convenient and is rapid, the extraction method is applicable to large-scale industrial production and is capable of keeping the activity of chemical components in guava peel to the greatest extent. The chemical active substance, which is extracted by virtue of the method, can significantly inhibit the growth of cancer cells, and the chemical active substance is good in oxidation resistance and antibacterial effect.

Description

technical field [0001] The invention belongs to the field of substance extraction, in particular to the extraction of guava active substances. Background technique [0002] Guava is a tropical fruit, widely distributed and planted in tropical and subtropical regions, such as Hainan, Guangdong, Guangxi, Taiwan, Yunnan, Guizhou, Sichuan, etc. in China. Guava is rich in nutrition, and its rich vitamin C has a good medicinal effect on treating diabetes. In addition, it reduces the risk of common cold illness, swollen gums, high blood pressure, obesity, diabetes and cancer. Guava can be eaten raw as fresh fruit or cooked, and cooked guava can be made into various sauces such as jams, jellies, and chutneys. Guava can also add flavor to various sauces, fruit salads, pies, puddings, ice cream, yogurt, and certain beverages. [0003] Guava not only has high value in food, but also has very high value in medicine. At present, the research on the medicinal components of guava is ma...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/61A61P35/00A61P39/06A61P31/04A61K131/00
CPCA61K36/61A61K2236/331
Inventor 李华斌陈永红李莎徐冬平王芳周通
Owner SUN YAT SEN UNIV
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