Eye drops

A technology of eye drops and longan meat, which is applied in the direction of drug delivery, drug combination, medical formula, etc., can solve the problems of low active ingredient content, inconvenient taking, and large dosage for patients, so as to achieve good practicability, solve the problem of low drying efficiency, Effect of improving drying efficiency

Inactive Publication Date: 2016-11-16
NANJING ZHENGKUAN MEDICAL TECH
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] The traditional Chinese medicine extraction method in the prior art has a rough and backward process, many impurities, and low content of active ingredients, which leads to excessive dosage for patients and is inconvenient to take, which seriously affects the clinical application of this product

Method used

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Examples

Experimental program
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Effect test

Embodiment 1

[0019] Take 10g wolfberry, 10g longan meat, 10g schisandra, 15g plantago, 6g Fushen, 6g polygala, 10g Ophiopogon japonicus, 3g Polygonatum odoratum, 30g angelica, 10g Bupleuri, 10g mulberry leaves, 10g Su stem, 10g poria cocos, wax gourd Skin 10g, kudzu root 10g, coix seed 10g, add 10 times the weight of medicinal materials in water, soak for 0.5h, decoct for 1 hour, filter, add medicinal residues in water 8 times the weight of medicinal materials, decoct for 1 hour, and filter out the medicinal liquid. Combine two decoction liquids, concentrate to 60°C relative density is 1.05, add ethanol to make the volume percentage of alcohol content reach 75%, stir, stand still, filter, when the filtrate is concentrated to 65°C relative density is 1.25, and recover ethanol , to obtain a concentrated solution, use supercritical extraction to obtain a supercritical extract, continue to concentrate, dry the concentrated solution, and prepare eye drops by a conventional method, and the dosage...

Embodiment 2

[0030] Take 10g wolfberry, 10g longan meat, 10g schisandra, 15g plantago, 6g Fushen, 6g polygala, 10g Ophiopogon japonicus, 3g Polygonatum odoratum, 30g angelica, 10g Bupleuri, 10g mulberry leaves, 10g Su stem, 10g poria cocos, wax gourd Skin 10g, kudzu root 10g, coix seed 10g, add 10 times the weight of medicinal materials in water, soak for 0.5h, decoct for 1 hour, filter, add medicinal residues in water 8 times the weight of medicinal materials, decoct for 1 hour, and filter out the medicinal liquid. Combine two decoction liquids, concentrate to 60°C relative density is 1.05, add ethanol to make the volume percentage of alcohol content reach 75%, stir, stand still, filter, when the filtrate is concentrated to 65°C relative density is 1.25, and recover ethanol , to obtain a concentrated solution, use supercritical extraction to obtain a supercritical extract, continue to concentrate, dry the concentrated solution, and prepare eye drops by a conventional method, and the dosage...

Embodiment 3

[0034] Take 10g wolfberry, 10g longan meat, 10g schisandra, 15g plantago, 6g Fushen, 6g polygala, 10g Ophiopogon japonicus, 3g Polygonatum odoratum, 30g angelica, 10g Bupleuri, 10g mulberry leaves, 10g Su stem, 10g poria cocos, wax gourd Skin 10g, kudzu root 10g, coix seed 10g, add 10 times the weight of medicinal materials in water, soak for 0.5h, decoct for 1 hour, filter, add medicinal residues in water 8 times the weight of medicinal materials, decoct for 1 hour, and filter out the medicinal liquid. Combine two decoction liquids, concentrate to 60°C relative density is 1.05, add ethanol to make the volume percentage of alcohol content reach 75%, stir, stand still, filter, when the filtrate is concentrated to 65°C relative density is 1.25, and recover ethanol , to obtain a concentrated solution, use supercritical extraction to obtain a supercritical extract, continue to concentrate, dry the concentrated solution, and prepare eye drops by a conventional method, and the dosage...

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Abstract

The invention provides eye drops. The eye drops are prepared by the following steps in accordance with a conventional method: soaking the following medicinal materials in water which is 10 times as much as the total weight of the medicinal materials for 0.5h: 10g of fruits of Chinese wolfberry, 10g of arillus longan, 10g of fruits of Chinese magnoliavine, 15g of semen plantaginis, 6g of poria with hostwood, 6g of radix polygalae, 10g of radix ophiopogonis, 3g of radix polygonati officinalis, 30g of radix angelicae sinensis, 10g of radix bupleuri, 10g of folium mori, 10g of caulis perllae, 10g of poria, 10g of Chinese waxgourd peels, 10g of radix puerariae and 10g of coix seeds; decocting the medicinal materials for 1h; conducting filtering; adding water which is 8 times as much as the total weight of the medicinal materials to dregs and conducting decocting for 1h; filtering medicine liquid, combining two times of decoction, and conducting concentrating until relative density is 1.05 at 60 DEG C; adding ethanol until the volume percentage of an alcohol content is 75%; conducting stirring, standing by and filtering; concentrating a filtrate until relative density is 1.25 at 65 DEG C, and recovering ethanol, so that a concentrated solution is obtained; conducting supercritical extraction, so that a supercritical extract is obtained; continuing to conduct concentrating; and drying a concentrated solution. The prepared eye drops are high in content of ferulic acid.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine extraction, in particular to an eye drop. Background technique [0002] The traditional Chinese medicine extraction method in the prior art has a rough and backward process, many impurities, and low content of active ingredients, which leads to excessive dosage for patients and is inconvenient to take, which seriously affects the clinical application of this product. Contents of the invention [0003] Purpose of the invention: In order to solve the above problems, the purpose of the present invention is to provide a kind of eye drops. [0004] Technical scheme: the purpose of the present invention is achieved by the following scheme: [0005] An eye drop, the preparation method is: take 10g of wolfberry, 10g of longan meat, 10g of schisandra, 15g of plantago, 6g of Fushen, 6g of polygala, 10g of Radix Polygonatum, 3g of Polygonatum odoratum, 30g of angelica, 10g of Bupleuri...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8994A61P27/10
CPCA61K9/0048A61K36/076A61K36/232A61K36/233A61K36/42A61K36/488A61K36/535A61K36/57A61K36/605A61K36/68A61K36/69A61K36/77A61K36/79A61K36/815A61K36/8968A61K36/8969A61K36/8994A61K2236/331A61K2236/37A61K2236/39A61K2236/51A61K2236/53A61K2300/00
Inventor 卞毓平
Owner NANJING ZHENGKUAN MEDICAL TECH
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