Method for Determination of Isothiazolinone Content in Kaisong Preservatives

Abstract

The invention provides a method for determining the content of isothiazolinone in a Kathon preservative and relates to the technical field of detection of matter content. According to the method provided by the invention, a chromatograph / mass spectrograph is replaced with distillation equipment, and a chemical titration method and a calculation formula are combined to inversely calculate the content of the isothiazolinone in the Kathon preservative. The determination method has simple steps; detection equipment used by the determination method is common equipment of a laboratory and the investment of the detection equipment is small; and the detection precision is relatively high and the price of consumable items used in a detection process is low, so that the method is economical and practical.

Description

technical field [0001] The invention relates to the technical field of substance content detection, in particular to a method for determining the content of isothiazolinone in Kaisong preservatives. Background technique [0002] Kaisong preservatives are also called Kasong preservatives, and the active ingredients are isothiazolinone compounds. Isothiazolinone is a general name for a class of derivatives, mainly 5-chloro-2-methyl-1-isothiazole A mixture of lin-3-one and 2-methyl-1-isothiazolin-3-one, in which 5-chloro-2-methyl-1-isothiazolin-3-one is abbreviated as CMIT, 2-methyl -1-isothiazolin-3-one is referred to as MIT. [0003] After Goerdeler and Mittler first proposed the preparation method of isothiazolinone in 1963, Rohm&Hass company has been studying it and using it as a biocide. Isothiazolinone has the advantages of high efficiency, broad spectrum, and environmental safety. It is an ideal biocide, which is widely used in petrochemical / daily chemical products and...

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Problems solved by technology

[0004] Prior to this, gas chromatography-mass spectrometry or high-performance liquid chromatography (HPLC) was usually used to determine the content of isothiazolinones in Kaisong preservatives. Although the above-mentioned determination methods have the advantages of high accuracy, the determination process requires The experimental equipment is expensive (mostly more than 100,000 yuan), and the consumables used are not cheap. If it is not a special external testing organization, the purchase of the above equipment and consumables is only used to detect the content of isothiazolinone in Kaisong preservatives. , obviously not cost-effective

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