Method for constructing prediction mathematic model for organ-at-risk adsorbed dose in intensity modulated radiation therapy

A technology of absorbed dose and mathematical model, applied in medical simulation, instrumentation, informatics, etc., can solve the problems of minimum absorbed dose, difficult planning and application of intensity-modulated radiotherapy, complicated methods, etc., achieving easy data, suitable for widespread application, simple method effect
CN106169028AActive Publication Date: 2016-11-30THE AFFILIATED HOSPITAL OF SOUTHWEST MEDICAL UNIV
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Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
THE AFFILIATED HOSPITAL OF SOUTHWEST MEDICAL UNIV
Publication Date
2016-11-30

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Abstract

The invention discloses a method for constructing a prediction mathematic model for organ-at-risk adsorbed dose in intensity modulated radiation therapy. The method comprises the steps of 1, dividing an organ-at-risk into n sub-organs, and obtaining the normalization volume Vn / VOAR of the n sub-organ; 2, obtaining the normalization adsorbed dose Dn10-n100 of the organ-at-risk according to an intensity modulated therapy plan; 3, obtaining the prediction mathematic model according to the normalization volume Vn / VOAR of the n sub-organ and normalization adsorbed dose Dn10-n100 of the organ-at-risk. According to the method, organ-at-risk adsorbed dose is predicted before making the intensity modulated therapy plan; the method is simple and practical, data are easy to acquire, the prediction mathematic model for organ-at-risk adsorbed dose in intensity modulated radiation therapy can be constructed by most radiotherapy units by means of the method based on an existing treatment plan system, and the method is suitable for wide application and popularization.
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Description

technical field

[0001] The invention relates to the technical field of medical radiotherapy, in particular to a method for constructing a mathematical model for predicting absorbed dose to organs at risk in intensity-modulated radiotherapy. Background technique

[0002] Tumor radiotherapy is a local treatment method that uses radiation to treat tumors. It is mainly used for malignant tumors. Statistics show that about 50%-70% of cancer patients need to receive radiation therapy to varying degrees. The basic purpose of radiotherapy is to increase the therapeutic gain ratio of radiotherapy, that is, to maximize the dose of radiation to the target area, kill tumor cells, and reduce or avoid unnecessary irradiation of surrounding normal tissues. Conformal radiation therapy is a more effective physical method to improve the treatment gain ratio. Intensity-modulated radiation therapy, that is, intensity-modulated conformal radiation therapy, is a type of conformal radiation ther...

Claims

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